PRICKLE4

PRICKLE4
Identifiers
Aliases	PRICKLE4, C6orf49, OBTP, OEBT, TOMM6, prickle planar cell polarity protein 4
External IDs	OMIM: 611389; MGI: 2685785; HomoloGene: 22752; GeneCards: PRICKLE4; OMA:PRICKLE4 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6p21.1 Start 41,780,782 bp End 41,787,452 bp
Gene location (Mouse) Chr. Chromosome 17 (mouse) Band 17|17 C Start 47,999,442 bp End 48,005,661 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad right lobe of thyroid gland right hemisphere of cerebellum spleen left lobe of thyroid gland apex of heart right uterine tube body of uterus myometrium Top expressed in white adipose tissue muscle tissue proximal tubule muscle of thigh quadriceps femoris muscle skeletal muscle tissue embryo urinary bladder striatum of neuraxis spermatocyte More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding molecular function actin binding muscle alpha-actinin binding Cellular component nucleus stress fiber Z discdkac filamentous actin Biological process biological process development of the heart actin cytoskeleton organization muscle structure development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 29964 381104 Ensembl ENSG00000278224 ENSMUSG00000096549 UniProt Q2TBC4 n/a RefSeq (mRNA) NM_013397 NM_017601 NM_001290337 RefSeq (protein) NP_037529 n/a Location (UCSC) Chr 6: 41.78 – 41.79 Mb Chr 17: 48 – 48.01 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Prickle-like protein 4 is a protein that in humans is encoded by the PRICKLE4 gene.

External links

• Human PRICKLE4 genome location and PRICKLE4 gene details page in the UCSC Genome Browser.
• Human TOMM6 genome location and TOMM6 gene details page in the UCSC Genome Browser.

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS (Dec 2005). "Transcriptome analysis of human gastric cancer". Mammalian Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
• Chassin D, Bénifla JL, Delattre C, Fernandez H, Ginisty D, Janneau JL, Prade M, Contesso G, Caillou B, Tournaire M (Oct 1994). "Identification of genes overexpressed in tumors through preferential expression screening in trophoblasts". Cancer Research. 54 (19): 5217–23. PMID 7923143.