// Workers AI · dad joke modeWhat did PEX11A say to its friend? "You're a perfect match

PEX11A
Identifiers
Aliases	PEX11A, PEX11-ALPHA, PMP28, hsPEX11p, peroxisomal biogenesis factor 11 alpha, PEX11alpha
External IDs	OMIM: 603866; MGI: 1338788; GeneCards: PEX11A
Gene location (Human)
Chr.	Chromosome 15 (human)
End	89,690,783 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	79,392,879 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; germinal epithelium; ; mucosa of transverse colon; ; parotid gland; ; adipose tissue; ; lactiferous gland; ; right lobe of liver; ; mucosa of sigmoid colon; ; palpebral conjunctiva; ; subcutaneous adipose tissue;
	Top expressed in
	salivary gland; ; lacrimal gland; ; brown adipose tissue; ; parotid gland; ; left lobe of liver; ; right kidney; ; submandibular gland; ; zygote; ; Paneth cell; ; proximal tubule;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; protein homodimerization activity;
Cellular component	integral component of membrane; peroxisomal membrane; peroxisome; membrane; integral component of peroxisomal membrane; protein-containing complex;
Biological process	regulation of peroxisome size; peroxisome membrane biogenesis; peroxisome organization; signal transduction; peroxisome fission; brown fat cell differentiation; regulation of lipid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	8800
	18631
	ENSG00000166821
	ENSMUSG00000030545
	O75192
	Q9Z211
	NM_003847; NM_001271572; NM_001271573
	NM_011068
	NP_001258501; NP_001258502; NP_003838
	NP_035198
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxisomal membrane protein 11A is a protein that in humans is encoded by the PEX11A gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000166821 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030545 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (Dec 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem. 273 (45): 29607–14. doi:10.1074/jbc.273.45.29607. PMID 9792670.
↑ "Entrez Gene: PEX11A peroxisomal biogenesis factor 11A".

Abe I, Okumoto K, Tamura S, Fujiki Y (1998). "Clofibrate-inducible, 28-kDa peroxisomal integral membrane protein is encoded by PEX11". FEBS Lett. 431 (3): 468–72. Bibcode:1998FEBSL.431..468A. doi:10.1016/S0014-5793(98)00815-1. PMID 9714566.
South ST, Gould SJ (1999). "Peroxisome Synthesis in the Absence of Preexisting Peroxisomes". J. Cell Biol. 144 (2): 255–66. doi:10.1083/jcb.144.2.255. PMC 2132891. PMID 9922452.
Sacksteder KA, Jones JM, South ST, et al. (2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. 148 (5): 931–44. doi:10.1083/jcb.148.5.931. PMC 2174547. PMID 10704444.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Shimizu M, Akter MH, Emi Y, et al. (2007). "Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair". J. Biochem. 139 (3): 563–73. doi:10.1093/jb/mvj053. PMID 16567422.
Orth T, Reumann S, Zhang X, et al. (2007). "The PEROXIN11 Protein Family Controls Peroxisome Proliferation in Arabidopsis". Plant Cell. 19 (1): 333–50. Bibcode:2007PlanC..19..333O. doi:10.1105/tpc.106.045831. PMC 1820951. PMID 17220199.

This article on a gene on human chromosome 15 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000166821 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030545 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9792670-5] Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (Dec 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem. 273 (45): 29607–14. doi:10.1074/jbc.273.45.29607. PMID 9792670.

[entrez-6] "Entrez Gene: PEX11A peroxisomal biogenesis factor 11A".

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// Workers AI · dad joke modeWhat did PEX11A say to its friend? "You're a perfect match

References

Further reading