PDZRN3

PDZRN3
Identifiers
Aliases	PDZRN3, LNX3, SEMACAP3, SEMCAP3, PDZ domain containing ring finger 3
External IDs	OMIM: 609729; MGI: 1933157; HomoloGene: 10328; GeneCards: PDZRN3; OMA:PDZRN3 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UHP, 1WH1
Enzyme activity
Gene location (Human)
Chr.	Chromosome 3 (human)
End	73,624,941 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	101,354,858 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; gastric mucosa; ; urethra; ; vastus lateralis muscle; ; seminal vesicula; ; cartilage tissue; ; saphenous vein; ; myocardium of left ventricle; ; right ventricle; ; tibia;
	Top expressed in
	molar; ; soleus muscle; ; tibialis anterior muscle; ; vastus lateralis muscle; ; gastrocnemius muscle; ; umbilical cord; ; atrioventricular valve; ; medial head of gastrocnemius muscle; ; triceps brachii muscle; ; sternocleidomastoid muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; metal ion binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; transferase activity;
Cellular component	neuromuscular junction; nucleus; nucleoplasm; cytosol; cytoplasm; cell junction; synapse;
Biological process	neuromuscular junction development; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	23024
	55983
	ENSG00000121440
	ENSMUSG00000035357
	Q9UPQ7
	Q69ZS0
	NM_015009; NM_001303139; NM_001303140; NM_001303141; NM_001303142
	NM_018884
	NP_001290068; NP_001290069; NP_001290070; NP_001290071; NP_055824
	NP_061372
	Wikidata
View/Edit Human	View/Edit Mouse

PDZ domain-containing RING finger protein 3 is a protein that in humans is encoded by the PDZRN3 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000121440 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035357 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
↑ "Entrez Gene: PDZRN3 PDZ domain containing RING finger 3".

Bach I, Rodriguez-Esteban C, Carrière C, et al. (1999). "RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex". Nat. Genet. 22 (4): 394–9. doi:10.1038/11970. PMID 10431247. S2CID 22326394.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Katoh M, Katoh M (2004). "Identification and characterization of PDZRN3 and PDZRN4 genes in silico". Int. J. Mol. Med. 13 (4): 607–13. doi:10.3892/ijmm.13.4.607. PMID 15010864.
Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry". Proteomics. 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402. S2CID 6773754.
Santin AD, Zhan F, Bellone S, et al. (2004). "Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy". Int. J. Cancer. 112 (1): 14–25. doi:10.1002/ijc.20408. PMID 15305371. S2CID 29845339.
Meyer G, Varoqueaux F, Neeb A, et al. (2005). "The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin". Neuropharmacology. 47 (5): 724–33. doi:10.1016/j.neuropharm.2004.06.023. PMID 15458844. S2CID 11771522.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000121440 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000035357 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10470851-5] Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.

[entrez-6] "Entrez Gene: PDZRN3 PDZ domain containing RING finger 3".

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PDZRN3

References

Further reading