// Workers AI · dad joke modeWhat did PDZD11 say to its date? "You're a gene-ius match

PDZD11
Identifiers
Aliases	PDZD11, AIPP1, PDZK11, PISP, PDZ domain containing 11
External IDs	OMIM: 300632; MGI: 1919871; HomoloGene: 9530; GeneCards: PDZD11; OMA:PDZD11 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WI2
Gene location (Human)
Chr.	X chromosome (human)
End	70,290,514 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	99,670,174 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; myocardium of left ventricle; ; parotid gland; ; lateral nuclear group of thalamus; ; hypothalamus; ; prefrontal cortex; ; cardiac muscle tissue of right atrium; ; nasal epithelium; ; substantia nigra; ; amygdala;
	Top expressed in
	right kidney; ; ventricular zone; ; yolk sac; ; morula; ; choroid plexus of fourth ventricle; ; medial ganglionic eminence; ; blastocyst; ; embryo; ; seminal vesicula; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein C-terminus binding; protein binding;
Cellular component	cytoplasm; extracellular region; cytosol; synapse; cell-cell junction; presynapse; basolateral plasma membrane;
Biological process	maintenance of epithelial cell apical/basal polarity; protein localization to basolateral plasma membrane; neurotransmitter secretion; biotin metabolic process; pantothenate metabolic process; antimicrobial humoral response; ion transmembrane transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	51248
	72621
	ENSG00000120509
	ENSMUSG00000015668
	Q5EBL8
	Q9CZG9
	NM_016484
	NM_028303; NM_001356384
NP_057568; NP_001357103; NP_001357104; NP_001357105; NP_001357106;
	NP_001357107
	NP_082579; NP_001343313
	Wikidata
View/Edit Human	View/Edit Mouse

PDZ domain-containing protein 11 is a protein that in humans is encoded by the PDZD11 gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000120509 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000015668 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
↑ Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
↑ "Entrez Gene: PDZD11 PDZ domain containing 11".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Goellner GM, DeMarco SJ, Strehler EE (2003). "Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants". Ann. N. Y. Acad. Sci. 986 (1): 461–71. Bibcode:2003NYASA.986..461G. doi:10.1111/j.1749-6632.2003.tb07230.x. PMID 12763866. S2CID 447365.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Stephenson SE, Dubach D, Lim CM, et al. (2005). "A single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasis". J. Biol. Chem. 280 (39): 33270–9. doi:10.1074/jbc.M505889200. hdl:10536/DRO/DU:30039503. PMID 16051599.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000120509 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000015668 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11042152-5] Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.

[pmid12975309-6] Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.

[entrez-7] "Entrez Gene: PDZD11 PDZ domain containing 11".

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[4]

[5]

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// Workers AI · dad joke modeWhat did PDZD11 say to its date? "You're a gene-ius match

References

Further reading