PAK1IP1

PAK1IP1
Identifiers
Aliases	PAK1IP1, MAK11, PIP1, WDR84, bA421M1.5, hPIP1, PAK1 interacting protein 1
External IDs	OMIM: 607811; MGI: 1915333; HomoloGene: 39574; GeneCards: PAK1IP1; OMA:PAK1IP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	10,709,782 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	41,166,491 bp
RNA expression pattern
	Top expressed in
	prostate; ; Achilles tendon; ; endometrium; ; islet of Langerhans; ; mucosa of esophagus; ; gonad; ; smooth muscle tissue; ; gastrocnemius muscle; ; monocyte; ; rectum;
	Top expressed in
	primary oocyte; ; transitional epithelium of urinary bladder; ; otic placode; ; epiblast; ; morula; ; morula; ; maxillary prominence; ; saccule; ; mandibular prominence; ; otic vesicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	nucleolus; nucleus;
Biological process	roof of mouth development; negative regulation of signal transduction; cell population proliferation; ribosomal large subunit biogenesis; regulation of signal transduction by p53 class mediator; ribosome biogenesis;
	Sources:Amigo / QuickGO
Orthologs
	55003
	68083
	ENSG00000111845; ENSG00000285226
	ENSMUSG00000038683
	Q9NWT1
	Q9DCE5
	NM_017906
	NM_026550
	NP_060376
	NP_080826
	Wikidata
View/Edit Human	View/Edit Mouse

p21-activated protein kinase-interacting protein 1 is an enzyme that in humans is encoded by the PAK1IP1 gene.^[5]^[6]

Interactions

PAK1IP1 has been shown to interact with PAK1.^[5]

References

1 2 3 ENSG00000285226 GRCh38: Ensembl release 89: ENSG00000111845, ENSG00000285226 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038683 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Xia C, Ma W, Stafford LJ, Marcus S, Xiong WC, Liu M (May 2001). "Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1". Proc Natl Acad Sci U S A. 98 (11): 6174–9. Bibcode:2001PNAS...98.6174X. doi:10.1073/pnas.101137298. PMC 33441. PMID 11371639.
↑ "Entrez Gene: PAK1IP1 PAK1 interacting protein 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 ENSG00000285226 GRCh38: Ensembl release 89: ENSG00000111845, ENSG00000285226 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038683 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11371639-5] 1 2 Xia C, Ma W, Stafford LJ, Marcus S, Xiong WC, Liu M (May 2001). "Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1". Proc Natl Acad Sci U S A. 98 (11): 6174–9. Bibcode:2001PNAS...98.6174X. doi:10.1073/pnas.101137298. PMC 33441. PMID 11371639.

[entrez-6] "Entrez Gene: PAK1IP1 PAK1 interacting protein 1".

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PAK1IP1

Interactions

References

Further reading