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Ozopromide

From Wikipedia, the free encyclopedia

Ozopromide
Identifiers
  • N-(2-oxoazepan-3-yl)pyrrolidine-2-carboxamide
PubChem CID
Chemical and physical data
FormulaC11H19N3O2
Molar mass225.292 g·mol−1
3D model (JSmol)
  • C1CCNC(=O)C(C1)NC(=O)C2CCCN2
  • InChI=1S/C11H19N3O2/c15-10-9(4-1-2-6-13-10)14-11(16)8-5-3-7-12-8/h8-9,12H,1-7H2,(H,13,15)(H,14,16)
  • Key:FBGWHFNNNZPNPZ-UHFFFAOYSA-N

Ozopromide (OPC) is a natural product isolated from ink from the common octopus Octopus vulgaris. It has antiinflammatory effects and inhibits the growth of cancer cells in vitro but has not yet been further researched.[1][2]

References

[edit]
  1. Hernández-Zazueta MS, Luzardo-Ocampo I, García-Romo JS, Noguera-Artiaga L, Carbonell-Barrachina ÁA, Taboada-Antelo P, et al. (May 2021). "Bioactive compounds from Octopus vulgaris ink extracts exerted anti-proliferative and anti-inflammatory effects in vitro". Food and Chemical Toxicology. 151 112119. doi:10.1016/j.fct.2021.112119. PMID 33722603.
  2. Hernández-Zazueta MS, García-Romo JS, Luzardo-Ocampo I, Carbonell-Barrachina ÁA, Taboada-Antelo P, Rosas-Burgos EC, et al. (July 2023). "N-(2-ozoazepan-3-yl)-pyrrolidine-2-carboxamide, a novel Octopus vulgaris ink-derived metabolite, exhibits a pro-apoptotic effect on A549 cancer cell line and inhibits pro-inflammatory markers". Food and Chemical Toxicology. 177 113829. doi:10.1016/j.fct.2023.113829. PMID 37225033.