NMD3

NMD3
Identifiers
Aliases	NMD3, CGI-07, NMD3 ribosome export adaptor
External IDs	OMIM: 611021; MGI: 2140103; HomoloGene: 6127; GeneCards: NMD3; OMA:NMD3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	161,253,532 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	69,663,706 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; germinal epithelium; ; skin of thigh; ; skin of hip; ; parotid gland; ; secondary oocyte; ; amniotic fluid; ; parietal pleura; ; visceral pleura; ; gingival epithelium;
	Top expressed in
	embryo; ; secondary oocyte; ; embryo; ; epiblast; ; primary oocyte; ; primitive streak; ; zygote; ; tail of embryo; ; morula; ; Paneth cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein-macromolecule adaptor activity; RNA binding; ribosomal large subunit binding;
Cellular component	nucleus; membrane; nucleolus; cytoplasm; nucleoplasm;
Biological process	protein transport; ribosomal large subunit export from nucleus; positive regulation of RNA biosynthetic process; positive regulation of protein localization to nucleolus; positive regulation of protein binding; transport;
	Sources:Amigo / QuickGO
Orthologs
	51068
	97112
	ENSG00000169251
	ENSMUSG00000027787
	Q96D46
	Q99L48
	NM_015938; NM_001320227
	NM_133787
	NP_001307156; NP_057022
	NP_598548
	Wikidata
View/Edit Human	View/Edit Mouse

60S ribosomal export protein NMD3 is a protein that in humans is encoded by the NMD3 gene.^[5]^[6]^[7]

Interactions

NMD3 has been shown to interact with XPO1.^[8]

Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Thomas F, Kutay U (2003). "Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway". J. Cell Sci. 116 (Pt 12): 2409–19. doi:10.1242/jcs.00464. PMID 12724356.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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