// Workers AI · dad joke modeWhat did MDN1 say to its date? You're one.

MDN1
Identifiers
Aliases	MDN1, Rea1, midasin AAA ATPase 1
External IDs	OMIM: 618200; MGI: 1926159; HomoloGene: 39689; GeneCards: MDN1; OMA:MDN1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6q15 Start 89,642,498 bp End 89,819,794 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4 A5|4 14.3 cM Start 32,657,119 bp End 32,775,217 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver gonad testicle cerebellar hemisphere right hemisphere of cerebellum nucleus accumbens putamen primary visual cortex caudate nucleus substantia nigra Top expressed in tail of embryo primitive streak epiblast genital tubercle morula spermatocyte otic placode embryo paraventricular nucleus of hypothalamus blastocyst More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding ATPase activity unfolded protein binding ATP binding nucleotide binding Cellular component nucleus intermediate filament cytoskeleton nucleolus membrane cytosol preribosome, large subunit precursor nucleoplasm cytoplasm Biological process rRNA processing ribosomal large subunit assembly protein-containing complex assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23195 100019 Ensembl ENSG00000112159 ENSG00000288121 ENSMUSG00000058006 UniProt Q9NU22 n/a RefSeq (mRNA) NM_014611 NM_001081392 NM_133874 NM_177666 RefSeq (protein) NP_055426 n/a Location (UCSC) Chr 6: 89.64 – 89.82 Mb Chr 4: 32.66 – 32.78 Mb PubMed search
Wikidata
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MDN1, midasin homolog (yeast) is a protein that in humans is encoded by the MDN1 gene. Midasin is a member AAA ATPase family.

Further reading

Garbarino JE, Gibbons IR (July 2002). "Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein". BMC Genomics. 3 18. doi:10.1186/1471-2164-3-18. PMC 117441. PMID 12102729. van de Wijngaart DJ, Dubbink HJ, Molier M, de Vos C, Trapman J, Jenster G (November 2009). "Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression". Molecular Endocrinology. 23 (11): 1776–1786. doi:10.1210/me.2008-0280. PMC 5419170. PMID 19762545.