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// Workers AI · dad joke modeWhat did labdatriene synthase say? "I'm a compound-ly funny enzyme

From Wikipedia, the free encyclopedia
Labdatriene synthase
Identifiers
EC no.4.2.3.99
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Labdatriene synthase (EC 4.2.3.99, OsKSL10 (gene)) is an enzyme with systematic name 9α-copalyl-diphosphate diphosphate-lyase ((12E)-9α-labda-8(17),12,14-triene-forming).[1] This enzyme catalyses the following chemical reaction

9α-copalyl diphosphate (12E)-9α-labda-8(17),12,14-triene + diphosphate

The enzyme from rice (Oryza sativa) also produces ent-sandaracopimara-8(14),15-diene from ent-copalyl diphosphate.

References

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  1. Morrone D, Hillwig ML, Mead ME, Lowry L, Fulton DB, Peters RJ (May 2011). "Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals". The Biochemical Journal. 435 (3): 589–95. doi:10.1042/bj20101429. PMC 3723722. PMID 21323642.
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