// Workers AI · dad joke modeWhat did IMPG1 say to its date? You're a pixel-fect match.

IMPG1
Identifiers
Aliases	IMPG1, GP147, IPM150, SPACR, VMD4, interphotoreceptor matrix proteoglycan 1, RP91
External IDs	OMIM: 602870; MGI: 1926876; HomoloGene: 1201; GeneCards: IMPG1; OMA:IMPG1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6q14.1 Start 75,921,114 bp End 76,072,678 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9 E1|9 43.99 cM Start 80,220,612 bp End 80,347,534 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle nucleus accumbens secondary oocyte caudate nucleus gonad putamen right hemisphere of cerebellum Brodmann area 9 right frontal lobe right lung Top expressed in neural layer of retina retinal pigment epithelium gastrula embryo epithelium of lens lumbar spinal ganglion semi-lunar valve left ventricle aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function extracellular matrix structural constituent Cellular component extracellular region extracellular matrix Biological process visual perception Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3617 63859 Ensembl ENSG00000112706 ENSMUSG00000032343 UniProt Q17R60 Q8R1W8 RefSeq (mRNA) NM_001563 NM_001282368 NM_022016 RefSeq (protein) NP_001269297 NP_001554 NP_071299 Location (UCSC) Chr 6: 75.92 – 76.07 Mb Chr 9: 80.22 – 80.35 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Interphotoreceptor matrix proteoglycan 1 is a protein that in humans is encoded by the IMPG1 gene.

Further reading

• Felbor U, Gehrig A, Sauer CG, et al. (1998). "Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies". Cytogenet. Cell Genet. 81 (1): 12–7. doi:10.1159/000015001. PMID 9691169. S2CID 46766267.
• Gehrig A, Felbor U, Kelsell RE, et al. (1998). "Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stargardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA), and North Carolina macular dystrophy (MCDR1)". J. Med. Genet. 35 (8): 641–5. doi:10.1136/jmg.35.8.641. PMC 1051388. PMID 9719369.
• Acharya S, Rayborn ME, Hollyfield JG (1998). "Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis". Glycobiology. 8 (10): 997–1006. doi:10.1093/glycob/8.10.997. PMID 9719680.
• Acharya S, Rodriguez IR, Moreira EF, et al. (1998). "SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan". J. Biol. Chem. 273 (47): 31599–606. doi:10.1074/jbc.273.47.31599. PMID 9813076.
• Kuehn MH, Hageman GS (2000). "Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan". Matrix Biol. 18 (5): 509–18. doi:10.1016/S0945-053X(99)00043-8. PMID 10601738.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
• van Lith-Verhoeven JJ, Hoyng CB, van den Helm B, et al. (2004). "The benign concentric annular macular dystrophy locus maps to 6p12.3-q16". Invest. Ophthalmol. Vis. Sci. 45 (1): 30–5. doi:10.1167/iovs.03-0392. PMID 14691150.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Abd El-Aziz MM, El-Ashry MF, Barragan I, et al. (2006). "Molecular genetic analysis of two functional candidate genes in the autosomal recessive retinitis pigmentosa, RP25, locus". Curr. Eye Res. 30 (12): 1081–7. doi:10.1080/02713680500351039. PMID 16354621. S2CID 26204316.