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From Wikipedia, the free encyclopedia
Helena Kandarova
Alma materSlovak University of Technology, Freie Universität Berlin
Known forAlternatives to animal testing
Awards
Scientific career
FieldsToxicology
Monika Schäfer-Korting

Helena Kandarova (Helena Kanďárová) is a Slovak toxicologist and scientific researcher specializing in vitro toxicology, 3D tissue engineering, and alternative methods to animal testing. She is recognized for her contributions to the development and validation of non-animal testing methods used in regulatory toxicology for chemicals, cosmetics, and medical devices.[1][2][3][4]

Early life and education

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Helena Kandarova studied at the Slovak University of Technology, Faculty of Chemical and Food Engineering in Bratislava during 1996 - 2001[5] and completed her doctoral studies at the Freie Universität Berlin (Doctoral advisor Prof. Monika Schäfer-Korting) and ZEBET at the BfR (Doctoral supervisor Dr. Manfred Liebsch) in 2006 [6], where her research focused on the development and validation of in vitro methods using reconstructed human tissue models for toxicological assessment.[7][8]

Career

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Kandarova began her professional career in the biotechnology sector, joining MatTek Corporation, and served as founder and Executive Director of its EU subsidiary between 2009 and 2018. In this role, she coordinated the technology transfer from the USA to the European facility, managed and supervised validation studies. She took an important role in the broad implementation of alternative methods in regulatory toxicology through the training programmes focused on topical toxicity. [9][10][11]

Since 2019, Kandarova has been affiliated with the Slovak Academy of Sciences, where she serves as Director and Senior Scientist at the Institute of Experimental Pharmacology and Toxicology within the Centre of Experimental Medicine. Her work at the institute has included the establishment and management of the SK-NETVAL laboratory dedicated to the development and validation of alternative methods, as well as participation in international research projects focused on new approach methodologies and alternatives to animal testing. [9][10][11] Kandarova has also held a position at the Institute of Biochemistry and Microbiology at the Faculty of Chemical and Food Technology at the Slovak Technical Universtity in Bratislava between 2020 and 2026, where she was teaching cell and tissue culture engineering. [12]

Kandarová has held leadership and advisory roles in several international scientific organisations, including:

Research and contributions

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Kandarova's research focuses on developing new approach methodologies, particularly in vitro models using reconstructed human tissues, to replace or reduce animal testing in toxicology. Her work includes:

  • Development and validation of 3D human tissue models for skin, eye, and phototoxicity testing
  • Integration of alternative methods into OECD and ISO regulatory guidelines
  • Risk and safety assessment of chemicals, cosmetics, and medical devices using non-animal approaches[9]

Kandarová has authored or co-authored more than 90 scientific publications in the field of toxicology.[13][11] Kandarová has contributed to numerous peer-reviewed publications in toxicology. Her work includes validation studies on alternative testing methods and safety evaluation using human tissue models.[14][15][16]

Awards and recognition

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Kandarova has received several international awards for her contributions to alternative toxicological methods, including:

References

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  1. 1 2 "Interview mit Helena Kandarova". Deutscher Tierschutzbund (in German). Retrieved 2026-04-08.
  2. ↑ Schmidt, Christian; Markus, Jan; Kandarova, Helena; Wiest, Joachim (2020). "Tissue-on-a-Chip: Microphysiometry with Human 3D Models on Transwell Inserts". Frontiers in Bioengineering and Biotechnology. 8 760. doi:10.3389/fbioe.2020.00760. PMC 7417452. PMID 32850693.
  3. ↑ "EARA | News - Funding stymies acceptance of non-animal testing". www.eara.eu. Retrieved 2026-04-08.
  4. ↑ https://www.researchgate.net/profile/Helena-Kandarova
  5. ↑ "STU Portal Absolventov". STU Portal Absolventov. Retrieved 2026-05-15.
  6. ↑ "Helena Kandarova: In 2006, Alumna Dr. Helena Kandarova completed her PhD at Freie Universität". Freie Universität Berlin Alumni Network. Retrieved 2026-05-15.{{cite web}}: CS1 maint: url-status (link)
  7. ↑ "The Björn Ekwall Memorial Award winners". www.bemf.eu. Retrieved 2026-04-10.
  8. ↑ "Keynote Speaker – Helena Kandarova". The ACTC. 2019-01-24. Retrieved 2026-04-10.
  9. 1 2 3 4 5 "Helena Kandárová". easac.eu. Retrieved 2026-04-10.
  10. 1 2 Award, ESET Science. "Výnimoční vedci posúvajú Slovensko o krok vpred | ESET Science Award". www.esetscienceaward.sk. Retrieved 2026-04-10.
  11. 1 2 3 "Helena Kanďárová získala prestížny grant pre výskum v oblasti inhalačnej toxicity". Centrum experimentálnej medicíny SAV, v. v. i. (in Slovak). Retrieved 2026-04-10.
  12. ↑ "Director of the Institute of CEM SAV in pop-science magazine Quark". Centre of Experimental Medicine of the SAS. Retrieved 2026-04-12.
  13. ↑ "Doerenkamp-Zbinden Award 2021". European Society of Toxicology In Vitro. 2021-09-06. Retrieved 2026-04-12.
  14. ↑ "ESTIV President, Dr. Helena Kandarova is the recipient of the 2022 EUROTOX Award Lecture". European Society of Toxicology In Vitro. 2022-09-22. Retrieved 2026-04-12.
  15. ↑ "Google Scholar". scholar.google.com. Retrieved 2026-04-12.
  16. ↑ Kandárová, Helena; Letašiová, Silvia (September 2011). "Alternative methods in toxicology: pre-validated and validated methods". Interdisciplinary Toxicology. 4 (3): 107–113. doi:10.2478/v10102-011-0018-6. ISSN 1337-9569. PMC 3203912. PMID 22058651.
  17. ↑ "Helena Kandarova featured in the PARCopedia editorial". ONTOX project. 2025-02-28. Retrieved 2026-04-12.
  18. ↑ "Scientific Committee". WC14 Seoul. Retrieved 2026-04-12.
  19. ↑ "Slovak scientists find a kinder way to test products without using animals". Slovak Spectator. 2025-04-30. Retrieved 2026-05-21.
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