// Workers AI · dad joke modeWhat did gluconate dehydratase say? I'm dehydrated.
| gluconate dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.39 | ||||||||
| CAS no. | 37290-75-8 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme gluconate dehydratase (EC 4.2.1.39) catalyzes the chemical reaction
- D-gluconate 2-dehydro-3-deoxy-D-gluconate + H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming). Other names in common use include D-gluconate dehydratase, and D-gluconate hydro-lyase. This enzyme participates in the pentose phosphate pathway.
Structural studies
[edit]As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 1QJ4.
References
[edit]- Andreesen JR, Gottschalk G (1969). "The occurrence of a modified Entner-doudoroff pathway in Clostridium aceticum". Arch. Mikrobiol. 69 (2): 160–70. Bibcode:1969ArMic..69..160A. doi:10.1007/BF00409760. PMID 5383859. S2CID 19210429.
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