// Workers AI · dad joke modeWhy was FAM107A a family favorite? It had a gene-ius reputation.

FAM107A
Identifiers
Aliases	FAM107A, DRR1, TU3A, family with sequence similarity 107 member A
External IDs	OMIM: 608295; MGI: 3041256; HomoloGene: 48509; GeneCards: FAM107A; OMA:FAM107A - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	58,627,610 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	14,173,499 bp
RNA expression pattern
	Top expressed in
	Region I of hippocampus proper; ; external globus pallidus; ; amygdala; ; right frontal lobe; ; C1 segment; ; optic nerve; ; putamen; ; nucleus accumbens; ; middle frontal gyrus; ; inferior olivary nucleus;
	Top expressed in
	otolith organ; ; utricle; ; vestibular membrane of cochlear duct; ; cerebellar vermis; ; lobe of cerebellum; ; lateral septal nucleus; ; medial dorsal nucleus; ; Epithelium of choroid plexus; ; inferior colliculi; ; globus pallidus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function; actin binding;
Cellular component	neuron projection; nucleus; nuclear speck; stress fiber; cytoplasm; focal adhesion; actin cytoskeleton; ruffle membrane; synapse; cytoskeleton; plasma membrane; membrane; cell junction; cell projection;
Biological process	regulation of growth; regulation of cell growth; actin filament polymerization; positive regulation of cell migration; positive regulation of protein ubiquitination; regulation of protein stability; cellular response to nutrient levels; regulation of actin cytoskeleton organization; cognition; actin filament bundle assembly; negative regulation of focal adhesion assembly; regulation of microtubule cytoskeleton organization; cellular response to glucocorticoid stimulus; negative regulation of long-term synaptic potentiation; negative regulation of G1/S transition of mitotic cell cycle; cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	11170
	268709
	ENSG00000168309
	ENSMUSG00000021750
	O95990
	Q78TU8
	NM_001076778; NM_001282713; NM_001282714; NM_007177
	NM_183187; NM_001360337; NM_001360338; NM_001360339
	NP_001070246; NP_001269642; NP_001269643; NP_009108; NP_001269643.1
	NP_001347266; NP_001347267; NP_001347268; NP_899010
	Wikidata
View/Edit Human	View/Edit Mouse

Protein FAM107A is a protein that in humans is encoded by the FAM107A gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000168309 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021750 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI (Feb 2000). "Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma". Genes Chromosomes Cancer. 27 (1): 1–10. doi:10.1002/(SICI)1098-2264(200001)27:1<1::AID-GCC1>3.0.CO;2-6. PMID 10564580. S2CID 24765920.
↑ Yamato T, Orikasa K, Fukushige S, Orikasa S, Horii A (Apr 2000). "Isolation and characterization of the novel gene, TU3A, in a commonly deleted region on 3p14.3→p14.2 in renal cell carcinoma". Cytogenet Cell Genet. 87 (3–4): 291–5. doi:10.1159/000015452. PMID 10702698. S2CID 34558356.
↑ "Entrez Gene: FAM107A family with sequence similarity 107, member A".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Kholodnyuk ID, Kozireva S, Kost-Alimova M, et al. (2006). "Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice". Int. J. Cancer. 119 (1): 99–107. doi:10.1002/ijc.21794. PMID 16432833. S2CID 27171340.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000168309 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021750 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10564580-5] Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI (Feb 2000). "Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma". Genes Chromosomes Cancer. 27 (1): 1–10. doi:10.1002/(SICI)1098-2264(200001)27:1<1::AID-GCC1>3.0.CO;2-6. PMID 10564580. S2CID 24765920.

[pmid10702698-6] Yamato T, Orikasa K, Fukushige S, Orikasa S, Horii A (Apr 2000). "Isolation and characterization of the novel gene, TU3A, in a commonly deleted region on 3p14.3→p14.2 in renal cell carcinoma". Cytogenet Cell Genet. 87 (3–4): 291–5. doi:10.1159/000015452. PMID 10702698. S2CID 34558356.

[entrez-7] "Entrez Gene: FAM107A family with sequence similarity 107, member A".

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// Workers AI · dad joke modeWhy was FAM107A a family favorite? It had a gene-ius reputation.

References

Further reading