Enterobacter kobei
This article coincides in timing and pattern with contributions by the same user which have been determined to be AI-generated, and has no significant contributions by other editors. It is presumed to have also been AI-generated, and may be assumed to violate Wikipedia's policies and guidelines. If no editor takes responsibility for it within a five-day grace period, this article may be deleted. To object to proposed deletion, an editor may take responsibility for the content and assume the onus to achieve consensus for its inclusion. Assuming responsibility requires that all content and its sources be closely reviewed, and reworked as needed, to ensure that they comply with polices and guidelines. This may involve checking that the cited sources support the content and are reliable, determining whether the content is due for inclusion, and rewriting the content to revise any tone issues and resolve possible copyright violations. Once this has been done, this template may be removed. The nominator also gave the following reason for this proposed deletion:
Find sources: "Enterobacter kobei" – news · newspapers · books · scholar · JSTOR Reviewer tools: guideline project (talk • log) Move: draft space The article may be deleted if this message remains in place for five days, i.e., after 05:49, 29 September 2026 (UTC). Nominator: Please consider notifying the author if active: {{subst:prodwarningLLM|Enterobacter kobei|concern=[[WP:LLMPRV|Presumptive removal of LLM-generated content]], see [[Wikipedia:AI noticeboard#User:Cytoscape]]. Please do not remove this tag without following [[WP:LLMPRVOBJ|the procedures for disputing presumptive removal of LLM-generated content]].}} ~~~~ |
| Enterobacter kobei | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Pseudomonadati |
| Phylum: | Pseudomonadota |
| Class: | Gammaproteobacteria |
| Order: | Enterobacterales |
| Family: | Enterobacteriaceae |
| Genus: | Enterobacter |
| Species: | E. kobei |
| Binomial name | |
| Enterobacter kobei Kosako et al. 1997[1] | |
Enterobacter kobei is a species of Gram-negative, facultatively anaerobic, motile, rod-shaped bacterium in the family Enterobacteriaceae. It belongs to the Enterobacter cloacae complex, whose members can be difficult to distinguish using routine phenotypic tests or 16S rRNA gene sequencing.[2] Strains have been recovered from human clinical specimens and environmental samples.[3][4]
Taxonomy
[edit]The specific epithet kobei means "of Kobe", referring to Kobe, Japan.[1] The type strain, NIH 1485-79 (DSM 13645; JCM 8580), was isolated from the blood of a patient with diabetes.[5]
Characteristics
[edit]Cells are Gram-negative, motile rods, and the species is facultatively anaerobic.[3][5] The type-strain culture has been reported to grow between 10 and 41 °C. Reported metabolic characteristics include fermentation of glucose and lactose, utilization of citrate, and reduction of nitrate.[5]
Species-level identification within the E. cloacae complex may require analysis of genes such as hsp60 or whole-genome sequencing. In a study of 183 clinical isolates of the complex collected from eight hospitals in South Korea, 25 isolates were identified as E. kobei by hsp60 sequence analysis.[2]
Clinical significance and antimicrobial resistance
[edit]Enterobacter kobei has been associated with hospital-acquired bloodstream and urinary tract infections. During an outbreak in a neonatal intensive care unit in Nepal, the bacterium was recovered from the blood cultures of 11 neonates, five of whom died. Whole-genome sequencing showed that 10 of the 11 isolates were clonal. The outbreak isolates carried antimicrobial resistance genes including blaAmpC and mcr-10 and displayed reduced susceptibility to carbapenems and colistin.[6]
Antimicrobial resistance genes do not necessarily produce the same susceptibility phenotype in every strain. An environmental strain isolated from a domestic kitchen sink in China carried plasmid-borne mcr-10.1 but remained susceptible to colistin; it was resistant to several other antibiotics, including cefazolin, cefoxitin, and fosfomycin.[4]
References
[edit]- 1 2 "Species: Enterobacter kobei". List of Prokaryotic names with Standing in Nomenclature. Leibniz Institute DSMZ. Retrieved 16 August 2026.
- 1 2 Ganbold, Michidmaral; Seo, Jungyu; Wi, Yu Mi; Kwon, Ki Tae; Ko, Kwan Soo (2023). "Species identification, antibiotic resistance, and virulence in Enterobacter cloacae complex clinical isolates from South Korea". Frontiers in Microbiology. 14 1122691. doi:10.3389/fmicb.2023.1122691. PMC 10076837. PMID 37032871.
- 1 2 Kosako, Yoshimasa; Tamura, Kazumichi; Sakazaki, Riichi; Miki, Kanzi (1996). "Enterobacter kobei sp. nov., a new species of the family Enterobacteriaceae resembling Enterobacter cloacae". Current Microbiology. 33 (4): 261–265. doi:10.1007/s002849900110. PMID 8824173.
- 1 2 Liu, Xuejuan; Li, Ping; Yan, Yong; Gao, Lei; Jia, Miaomiao; Wang, Shan; He, Peiyan; Zhu, Guoying; Chen, Zhongwen (2026). "First report and genomic characterization of an mcr-10.1-carrying Enterobacter kobei strain isolated from a domestic kitchen sink in China". BMC Microbiology. 26 673. doi:10.1186/s12866-026-05205-2.
- 1 2 3 "Enterobacter kobei DSM 13645". BacDive. Leibniz Institute DSMZ. Retrieved 16 August 2026.
- ↑ Manandhar, Sulochana; Nguyen, Quynh; Pham, Duc T.; Amatya, Prativa; Rabaa, Maia; Dongol, Sabina; Basnyat, Buddha; Dixit, Sameer Mani; Baker, Stephen; Karkey, Abhilasha (2022). "A fatal outbreak of neonatal sepsis caused by mcr-10-carrying Enterobacter kobei in a tertiary care hospital in Nepal". Journal of Hospital Infection. 125: 60–66. doi:10.1016/j.jhin.2022.03.015. PMID 35460799.