ERGIC3

ERGIC3
Identifiers
Aliases	ERGIC3, C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84, dJ477O4.2, ERGIC and golgi 3, C2orf47
External IDs	OMIM: 616971; MGI: 1913616; GeneCards: ERGIC3
Gene location (Human)
Chr.	Chromosome 20 (human)
End	35,557,634 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	155,860,199 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; right testis; ; left testis; ; stromal cell of endometrium; ; olfactory zone of nasal mucosa; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; canal of the cervix; ; mucosa of transverse colon; ; left ovary;
	Top expressed in
	molar; ; neural layer of retina; ; yolk sac; ; choroid plexus of fourth ventricle; ; right kidney; ; dentate gyrus of hippocampal formation granule cell; ; external carotid artery; ; vestibular sensory epithelium; ; epithelium of lens; ; tail of embryo;
	More reference expression data
	More reference expression data
Orthologs
Databases	NCBI: entry; OMA: entry
	51614
	66366
	ENSG00000125991
	ENSMUSG00000005881
	Q9Y282
	Q9CQE7
	NM_015966; NM_198398
	NM_025516; NM_001356413; NM_001356414
	NP_057050; NP_938408
	NP_079792; NP_001343342; NP_001343343
	Wikidata
View/Edit Human	View/Edit Mouse

Endoplasmic reticulum-Golgi intermediate compartment protein 3 is a protein that in humans is encoded by the ERGIC3 gene.^[5]^[6] It has been reported to be regulated by micro RNAs and may be important in a cancer.^[7]^[8]

It is a member of the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) family.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000125991 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005881 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (August 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Research. 10 (5): 703–713. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: ERGIC3 ERGIC and golgi 3".
↑ Zhang LY, Liu M, Li X, Tang H (February 2013). "miR-490-3p modulates cell growth and epithelial to mesenchymal transition of hepatocellular carcinoma cells by targeting endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3)". The Journal of Biological Chemistry. 288 (6): 4035–4047. doi:10.1074/jbc.M112.410506. PMC 3567655. PMID 23212913.
↑ Lin QH, Zhang KD, Duan HX, Liu MX, Wei WL, Cao Y (October 2015). "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer". Cancer Science. 106 (10): 1463–1473. doi:10.1111/cas.12741. PMC 4638005. PMID 26177443.

Scanlan MJ, Gout I, Gordon CM, Williamson B, Stockert E, Gure AO, et al. (March 2001). "Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression". Cancer Immunity. 1: 4. PMID 12747765.
Breuza L, Halbeisen R, Jenö P, Otte S, Barlowe C, Hong W, et al. (November 2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46". The Journal of Biological Chemistry. 279 (45): 47242–47253. doi:10.1074/jbc.M406644200. PMID 15308636.
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, et al. (2005). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Research. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
Nishikawa M, Kira Y, Yabunaka Y, Inoue M (2007). "Identification and characterization of endoplasmic reticulum-associated protein, ERp43". Gene. 386 (1–2): 42–51. doi:10.1016/j.gene.2006.06.030. PMID 17020792.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000125991 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005881 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Lai_2000-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (August 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Research. 10 (5): 703–713. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-6] "Entrez Gene: ERGIC3 ERGIC and golgi 3".

[ZhangLiu2013-7] Zhang LY, Liu M, Li X, Tang H (February 2013). "miR-490-3p modulates cell growth and epithelial to mesenchymal transition of hepatocellular carcinoma cells by targeting endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3)". The Journal of Biological Chemistry. 288 (6): 4035–4047. doi:10.1074/jbc.M112.410506. PMC 3567655. PMID 23212913.

[LinZhang2015-8] Lin QH, Zhang KD, Duan HX, Liu MX, Wei WL, Cao Y (October 2015). "ERGIC3, which is regulated by miR-203a, is a potential biomarker for non-small cell lung cancer". Cancer Science. 106 (10): 1463–1473. doi:10.1111/cas.12741. PMC 4638005. PMID 26177443.

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ERGIC3

References

Further reading