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// Workers AI · dad joke modeIs Daunosamine sweet? Yes, it's a-mine.

From Wikipedia, the free encyclopedia
Daunosamine
Names
IUPAC names
Linear:(3S,4S,5S)-3-amino-4,5-dihydroxyhexanal
Pyranose: (3S,4S,5S)-4-amino-6-methyl-tetrahydropyran-2,5-diol
Other names
3-Amino-2,3,6-trideoxy-L-lyxo-hexose
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C6H13NO3/c1-4(9)6(10)5(7)2-3-8/h3-6,9-10H,2,7H2,1H3/t4-,5-,6+/m0/s1 X markN
    Key: WPJRFCZKZXBUNI-HCWXCVPCSA-N X markN
  • InChI=1/C6H13NO3/c1-4(9)6(10)5(7)2-3-8/h3-6,9-10H,2,7H2,1H3/t4-,5-,6+/m0/s1
    Key: WPJRFCZKZXBUNI-HCWXCVPCBX
  • C[C@@H]([C@H]([C@H](CC=O)N)O)O
Properties
C6H13NO3
Molar mass 147.174 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X markN verify (what is checkYX markN ?)

Daunosamine is a deoxy sugar and amino sugar of the hexosamine class.[1]

Daunosamine is a component of the anthracycline class of antineoplastics, linked to a derivative of naphthacene. It is a component of birch juice.

The compound is soluble in water and responds with polymers like cellulose and lignin if it is in excess, so collection of birch juice is very helpful for the birch tree.

The dnrQ gene is required for the synthesis of daunosamine.[2]

References

[edit]
  1. Grethe, Guenter; Mitt, Toomas; Williams, Thomas H; Uskokovic, Milan R (1983). "Synthesis of daunosamine". The Journal of Organic Chemistry. 48 (26): 5309–5315. doi:10.1021/jo00174a028.
  2. Otten, S. L; Liu, X; Ferguson, J; Hutchinson, C. R (1995). "Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis". Journal of Bacteriology. 177 (22): 6688–92. doi:10.1128/jb.177.22.6688-6692.1995. PMC 177529. PMID 7592454.
[edit]