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// Workers AI · dad joke modeWho's Daniel P. Kelly? A guy with a lot of 'pull' like gravity, but less known.

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From Wikipedia, the free encyclopedia
Daniel P. Kelly
October, 2016
Born1955 in Fukuoka, Japan (US Army Base)
Alma materStevenson High School (Lincolnshire, Illinois) (1974)

University of Illinois (B.S., 1978)

University of Illinois College of Medicine, Chicago, Illinois (M.D., 1982)
Known forKnown for his contributions to the transcriptional control of mitochondrial function and the metabolic origins of heart disease.
AwardsAmerican Heart Association (BCVS) Distinguished Achievement Award (2008)

American Heart Association Basic Science Prize (2009)

Peter Harris Distinguished Scientist Award of the International Society for Heart Research (ISHR) (2023)
Scientific career
FieldsBiomedical Research
InstitutionsUniversity of Pennsylvania

Children's Hospital of Philadelphia

Sanford Burnham Prebys Medical Discovery Institute

Washington University in St. Louis

Daniel P. Kelly (born 1955) is Director of the Penn[1][2] and CHOP[3][4] Cardiovascular Institutes (CVI) and the Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases at the University of Pennsylvania Perelman School of Medicine and the Rachel Ash Presidential Professor at Children's Hospital of Philadelphia (CHOP). He is a cardiologist and physician-scientist recognized for his contributions to the transcriptional control of mitochondrial function and the metabolic origins of heart disease.

Education and Career

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Kelly obtained his medical degree from the University of Illinois College of Medicine, internal medicine residency training at Barnes Hospital in St. Louis, and clinical cardiology and research training at Washington University School of Medicine (WUSM) in St. Louis. He joined the WUSM faculty in 1989 and rapidly moved up the ranks to Professor of Medicine, Molecular Biology & Pharmacology, and Pediatrics, Chief of the Cardiovascular Division[5], Alumni Endowed Professor of Cardiovascular Diseases.[6] and first Director of the Center for Cardiovascular Research. In 2008, Kelly assumed the role of founding Scientific Director for the Sanford Burnham Prebys Medical Discovery Institute[7] site in Orlando, Florida. In August 2017, he moved to the University of Pennsylvania where he was named Director of the Penn Cardiovascular Institute (CVI). In 2022, Kelly also assumed the position of founding Director of a new CVI at Children's Hospital of Philadelphia (CHOP) with the mission of addressing unmet needs in cardiovascular health and disease throughout the lifespan.

Research

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Kelly's [8][9] research interests stem from an early fascination with rare inborn errors in mitochondrial metabolism in children which cause sudden death and heart failure. He defined the genetic basis for a common inborn error in mitochondrial fatty acid oxidation, work that led to the development of practical screening tests to detect risk for sudden death in newborns. His work defined a master regulatory axis that controls fuel metabolism in heart through pioneering studies on nuclear receptors including the peroxisome proliferator-activated receptors (PPARs), estrogen-related receptors (ERRs), and their transcriptional coactivators. Kelly and his team found that the failing heart begins to rely on ketone bodies as a fuel, work that has led to first in human studies aimed at assessing ketone supplementation in patients with heart failure. He has mentored over 65 MD, PhD, and MD-PhD graduate and post-graduate trainees.

Awards and Honors

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Kelly has been elected to the American Society of Clinical Investigation (Council Member, 2002–2005),  Association of American Physicians (Council Member, 2017 - 2023; President, 2022–2023)[10][11], Association of University of Cardiologists, Association of Professors of Cardiology and the International Society for Heart Research (ISHR, Council Member, 2018 - 2024).  He is a recipient of a Lucille Markey Scholar Award[12], March of Dimes Basal O’Connor Scholar Award, the American Heart Association (AHA) Established Investigator Award, AHA Basic Science Prize, and AHA Distinguished Achievement Award[13], and the ISHR Peter Harris Distinguished Scientist Award.[14] He serves, or has served, on the Editorial Boards of Genes & Development, Circulation, Circulation Research, The Journal of Clinical Investigation, and the Journal of the American College of Cardiology: Basic to Translational Science.

References

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  1. ↑ "Penn Medicine Appoints Daniel Kelly, MD, New Director of the Cardiovascular Institute | Newswise". www.newswise.com. Retrieved 2026-07-09.
  2. ↑ "History and Leadership | Cardiovascular Institute | Perelman School of Medicine at the University of Pennsylvania". www.med.upenn.edu. Retrieved 2026-07-09.
  3. ↑ The Children's Hospital of Philadelphia. "Children's Hospital of Philadelphia Launches Research Institute Dedicated to Advancing the Care of Pediatric Cardiovascular Diseases". Children's Hospital of Philadelphia. Archived from the original on 2026-05-08. Retrieved 2026-07-09.
  4. ↑ "CHOP Cardiovascular Institute". CHOP Research Institute. Retrieved 2026-07-09.
  5. ↑ "History". Cardiovascular Division. Retrieved 2026-07-09.
  6. ↑ Duenke, Ken (April 28, 2005). "Kelly named alumni professor of cardiovascular diseases".
  7. ↑ "Daniel Kelly, M.D." August 12, 2011 – via YouTube.
  8. ↑ "Kelly Laboratory | Cardiovascular Institute | Perelman School of Medicine at the University of Pennsylvania". www.med.upenn.edu.
  9. ↑ "Daniel P Kelly | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of Pennsylvania". www.med.upenn.edu.
  10. ↑ "Association of American Physicians". aap-online.org.
  11. ↑ Kelly, Daniel P. (January 2, 2024). "2023 Association of American Physicians Presidential AddressReplenishing the physician-scientist pipeline in the post–late bloomer era". www.jci.org.
  12. ↑ "Read" – via www.nationalacademies.org.
  13. ↑ "Council on Basic Cardiovascular Sciences Distinguished Achievement Award". professional.heart.org.
  14. ↑ "The Peter Harris Distinguished Scientist Award 2023" (PDF). Archived from the original (PDF) on 2024-04-19.
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