// Workers AI · dad joke modeWhat did CPNE7 say to its date? "You're a byte above the rest

CPNE7
Identifiers
Aliases	CPNE7, copine 7
External IDs	OMIM: 605689; MGI: 2142747; HomoloGene: 65128; GeneCards: CPNE7; OMA:CPNE7 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16q24.3 Start 89,575,758 bp End 89,597,246 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8|8 E1 Start 123,844,113 bp End 123,861,921 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus stromal cell of endometrium parotid gland pituitary gland cingulate gyrus anterior cingulate cortex anterior pituitary right frontal lobe hypothalamus dorsal motor nucleus of vagus nerve Top expressed in subiculum dentate gyrus of hippocampal formation granule cell primary visual cortex hippocampus proper medial dorsal nucleus superior frontal gyrus lateral septal nucleus anterior amygdaloid area nucleus of stria terminalis subdivision of hippocampus More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding transporter activity calcium-dependent phospholipid binding Cellular component cytoplasm plasma membrane extracellular exosome membrane nucleus Biological process cellular response to calcium ion glycerophospholipid biosynthetic process lipid metabolism transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27132 102278 Ensembl ENSG00000178773 ENSMUSG00000034796 UniProt Q9UBL6 Q0VE82 RefSeq (mRNA) NM_014427 NM_153636 NM_170684 RefSeq (protein) NP_055242 NP_705900 NP_733785 Location (UCSC) Chr 16: 89.58 – 89.6 Mb Chr 8: 123.84 – 123.86 Mb PubMed search
Wikidata
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Copine 7 is a protein that in humans is encoded by the CPNE7 gene.

Function

This gene encodes a member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains and one von Willebrand factor A domain. The encoded protein may be involved in membrane trafficking. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.