CAMK1G

CAMK1G
Identifiers
Aliases	CAMK1G, CLICK3, CLICKIII, VWS1, dJ272L16.1, calcium/calmodulin dependent protein kinase IG
External IDs	OMIM: 614994; MGI: 2388073; HomoloGene: 48706; GeneCards: CAMK1G; OMA:CAMK1G - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JAM
Enzyme activity
Gene location (Human)
Chr.	Chromosome 1 (human)
End	209,613,939 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	193,052,606 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 10; ; right frontal lobe; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex; ; nucleus accumbens; ; middle frontal gyrus; ; Region I of hippocampus proper; ; superior frontal gyrus;
	Top expressed in
	ventromedial nucleus; ; superior frontal gyrus; ; visual cortex; ; primary visual cortex; ; olfactory tubercle; ; pontine nuclei; ; primary motor cortex; ; central gray substance of midbrain; ; nucleus accumbens; ; nucleus of stria terminalis;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; catalytic activity; ATP binding; kinase activity; calmodulin-dependent protein kinase activity; calmodulin binding;
Cellular component	cytoplasm; calcium- and calmodulin-dependent protein kinase complex; neuron projection; Golgi membrane; plasma membrane; Golgi apparatus; membrane; endomembrane system; intracellular anatomical structure;
Biological process	protein phosphorylation; metabolism; phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	57172
	215303
	ENSG00000008118
	ENSMUSG00000016179
	Q96NX5
	Q91VB2
	NM_020439
	NM_144817
	NP_065172
	NP_659066
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium/calmodulin dependent protein kinase IG is a protein that in humans is encoded by the CAMK1G gene.^[5]

Function

This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is not known. [provided by RefSeq, Jul 2008].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000008118 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000016179 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Calcium/calmodulin dependent protein kinase IG". Retrieved 2018-08-28.

Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Segi E, Arakawa Y, Furuyashiki T, Narumiya S, Bito H (May 2003). "Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)". J. Biol. Chem. 278 (20): 18597–605. doi:10.1074/jbc.M300578200. PMID 12637513.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
Pang ZP, Xu W, Cao P, Südhof TC (October 2010). "Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons". J. Biol. Chem. 285 (44): 33930–9. doi:10.1074/jbc.M110.150151. PMC 2962493. PMID 20729199.
Deng M, Wei L, Zuo X, Tian Y, Xie F, Hu P, Zhu C, Yu F, Meng Y, Wang H, Zhang F, Ma H, Ye R, Cheng H, Du J, Dong W, Zhou S, Wang C, Wang Y, Wang J, Chen X, Sun Z, Zhou N, Jiang Y, Liu X, Li X, Zhang N, Liu N, Guan Y, Han Y, Han Y, Lv X, Fu Y, Yu H, Xi C, Xie D, Zhao Q, Xie P, Wang X, Zhang Z, Shen L, Cui Y, Yin X, Cheng H, Liang B, Zheng X, Lee TM, Chen G, Zhou F, Veldink JH, Robberecht W, Landers JE, Andersen PM, Al-Chalabi A, Shaw C, Liu C, Tang B, Xiao S, Robertson J, Zhang F, van den Berg LH, Sun L, Liu J, Yang S, Ju X, Wang K, Zhang X (June 2013). "Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis". Nat. Genet. 45 (6): 697–700. doi:10.1038/ng.2627. PMID 23624525. S2CID 7924012.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000008118 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000016179 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Calcium/calmodulin dependent protein kinase IG". Retrieved 2018-08-28.

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CAMK1G

Function

References

Further reading