BET1
BET1 homolog is a protein that in humans is encoded by the BET1 gene.[5][6][7]
This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex. The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.[7]
References
[edit]- 1 2 3 GRCh38: Ensembl release 89: ENSG00000105829 – Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032757 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, et al. (December 1997). "The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus". The Journal of Cell Biology. 139 (5): 1157–1168. doi:10.1083/jcb.139.5.1157. PMC 2140212. PMID 9382863.
- ↑ Waters MG, Pfeffer SR (November 1999). "Membrane tethering in intracellular transport". Current Opinion in Cell Biology. 11 (4): 453–459. doi:10.1016/S0955-0674(99)80065-9. PMID 10449330.
- 1 2 "Entrez Gene: BET1 BET1 homolog (S. cerevisiae)".
Further reading
[edit]- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport". The Journal of Biological Chemistry. 276 (29): 27480–27487. doi:10.1074/jbc.M102786200. PMID 11323436.
- Sanger Centre T, Washington University Genome Sequencing Cente T (November 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell. 89 (1): 149–158. doi:10.1016/S0092-8674(00)80191-9. PMID 9094723. S2CID 8682509.
- Hay JC, Hirling H, Scheller RH (1996). "Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus". The Journal of Biological Chemistry. 271 (10): 5671–5679. doi:10.1074/jbc.271.10.5671. PMID 8621431.
External links
[edit]- BET1 human gene location in the UCSC Genome Browser.
- BET1 human gene details in the UCSC Genome Browser.
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