BATF2

BATF2
Identifiers
Aliases	BATF2, SARI, basic leucine zipper ATF-like transcription factor 2
External IDs	OMIM: 614983; MGI: 1921731; GeneCards: BATF2
Gene location (Human) Chr. Chromosome 11 (human) Band 11q13.1 Start 64,987,945 bp End 64,997,018 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 A Start 6,191,013 bp End 6,222,506 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell oocyte mucosa of transverse colon gonad secondary oocyte testicle spleen appendix apex of heart body of pancreas Top expressed in intestinal villus jejunum mucous cell of stomach duodenum crypt of lieberkuhn of small intestine colon left colon ileum intercostal muscle embryo More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding Cellular component nucleus Biological process regulation of transcription by RNA polymerase II cell differentiation regulation of transcription, DNA-templated transcription, DNA-templated myeloid dendritic cell differentiation defense response to protozoan Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 116071 74481 Ensembl ENSG00000168062 ENSMUSG00000039699 UniProt Q8N1L9 Q8R1H8 RefSeq (mRNA) NM_001300807 NM_001300808 NM_138456 NM_028967 NM_001356604 NM_001379529 RefSeq (protein) NP_001287736 NP_001287737 NP_612465 NP_083243 NP_001343533 NP_001366458 Location (UCSC) Chr 11: 64.99 – 65 Mb Chr 19: 6.19 – 6.22 Mb PubMed search
Wikidata
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Basic leucine zipper transcription factor, ATF-like 2 is a protein that, in humans, is encoded by the BATF2 gene.

Further reading

• Ma H, Liang X, Chen Y, Pan K, Sun J, Wang H, et al. (February 2011). "Decreased expression of BATF2 is associated with a poor prognosis in hepatocellular carcinoma". International Journal of Cancer. 128 (4): 771–777. doi:10.1002/ijc.25407. PMID 20473897.
• Dash R, Su ZZ, Lee SG, Azab B, Boukerche H, Sarkar D, et al. (August 2010). "Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1". Oncogene. 29 (31): 4412–4423. doi:10.1038/onc.2010.194. PMID 20531301.
• Huang Q, Li XQ, Yang Y, Huang SA (August 2011). "[Influence of BCR-ABL inhibitor STI571 on SARI expression in K562 cells]". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 19 (4): 865–868. PMID 21867603.
• Su ZZ, Lee SG, Emdad L, Lebdeva IV, Gupta P, Valerie K, et al. (December 2008). "Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN)". Proceedings of the National Academy of Sciences of the United States of America. 105 (52): 20906–20911. Bibcode:2008PNAS..10520906S. doi:10.1073/pnas.0807975106. PMC 2634918. PMID 19074269.
• Wang C, Su Y, Zhang L, Wang M, You J, Zhao X, et al. (2012). "The function of SARI in modulating epithelial-mesenchymal transition and lung adenocarcinoma metastasis". PLOS ONE. 7 (9) e38046. Bibcode:2012PLoSO...738046W. doi:10.1371/journal.pone.0038046. PMC 3458851. PMID 23049725.
• Wenig JA (May 1990). "Os trigonum syndrome". Journal of the American Podiatric Medical Association. 80 (5): 278–282. doi:10.7547/87507315-80-5-278. PMID 2366175.
• Huang Q, Yang Y, Li X, Huang S (December 2011). "Transcription suppression of SARI (suppressor of AP-1, regulated by IFN) by BCR-ABL in human leukemia cells". Tumour Biology. 32 (6): 1191–1197. doi:10.1007/s13277-011-0222-1. PMID 21892628. S2CID 21309704.