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// Workers AI · dad joke modeWhat did Avermitilol synthase say? "I'm bonded to my work".

From Wikipedia, the free encyclopedia
Avermitilol synthase
Identifiers
EC no.4.2.3.96
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Avermitilol synthase (EC 4.2.3.96) is an enzyme with systematic name avermitilol hydrolase (cyclizing, avermitilol-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate + H2O avermitilol + diphosphate

This enzyme requires Mg2+.

References

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  1. Chou WK, Fanizza I, Uchiyama T, Komatsu M, Ikeda H, Cane DE (July 2010). "Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol". Journal of the American Chemical Society. 132 (26): 8850–1. Bibcode:2010JAChS.132.8850C. doi:10.1021/ja103087w. PMC 2904616. PMID 20536237.
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