ARHGAP44

ARHGAP44
Identifiers
Aliases	ARHGAP44, NPC-A-10, RICH2, Rho GTPase activating protein 44
External IDs	OMIM: 617716; MGI: 2144423; HomoloGene: 65284; GeneCards: ARHGAP44; OMA:ARHGAP44 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p12 Start 12,789,498 bp End 12,991,643 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B3 Start 64,892,865 bp End 65,053,787 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lateral nuclear group of thalamus Brodmann area 23 middle temporal gyrus buccal mucosa cell germinal epithelium primary visual cortex cerebellar cortex cerebellar hemisphere prefrontal cortex right hemisphere of cerebellum Top expressed in medial vestibular nucleus pontine nuclei deep cerebellar nuclei substantia nigra medial dorsal nucleus medial geniculate nucleus lateral geniculate nucleus dorsal tegmental nucleus piriform cortex primary motor cortex More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding phospholipid binding GTPase activator activity Cellular component cytoplasm recycling endosome cytosol cell junction endosome dendritic spine cell projection synapse leading edge membrane glutamatergic synapse intracellular anatomical structure postsynaptic density presynaptic active zone Biological process positive regulation of GTPase activity regulation of small GTPase mediated signal transduction signal transduction exocytosis regulation of actin cytoskeleton organization regulation of GTPase activity regulation of dendritic spine morphogenesis modification of dendritic spine neurotransmitter receptor transport, endosome to postsynaptic membrane negative regulation of Rac protein signal transduction modification of postsynaptic structure regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9912 216831 Ensembl ENSG00000006740 ENSMUSG00000033389 UniProt Q17R89 Q5SSM3 RefSeq (mRNA) NM_014859 NM_001321164 NM_001321166 NM_001321167 NM_001321168 NM_001099288 NM_175003 RefSeq (protein) NP_001308093 NP_001308095 NP_001308096 NP_001308097 NP_055674 NP_001092758 NP_778168 NP_001395152 NP_001395153 NP_001395155 NP_001395157 Location (UCSC) Chr 17: 12.79 – 12.99 Mb Chr 11: 64.89 – 65.05 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Rho GTPase activating protein 44 is a protein in humans that is encoded by the ARHGAP44 gene.

External links

• Human ARHGAP44 genome location and ARHGAP44 gene details page in the UCSC Genome Browser.

Further reading

• Sarowar T, Grabrucker S, Föhr K, Mangus, Eckert M, Bockmann J, Boeckers TM, Grabrucker AM (2016). "Enlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2". Molecular Brain. 9 (28): 28. doi:10.1186/s13041-016-0206-6. PMC 4788860. PMID 26969129.