// Workers AI · dad joke modeDoes WuXi AppTec have a test? Yes, an app-lication.
| Type | Public |
|---|---|
| |
| Industry | Contract Research Organizations Pharmaceutical Biopharmaceutical Medical Devices |
| Founded | 2000 |
| Headquarters | Shanghai, China |
Key people | Ge Li |
| Website | www |
WuXi AppTec Co., Ltd. (WuXi is pronounced as Wu-shee) is a Chinese provider of contract research, development, and manufacturing, services for the pharmaceutical and life-sciences industry, headquartered in Shanghai, China. The company operates research and manufacturing facilities in Asia, North America, and Europe.
Founded in 2000 by chemist Ge Li as WuXi PharmaTech, the company expanded through acquisitions and re‑listings in 2018 after a 2015 take‑private. It produces a large part of the ingredients used in treatments for illnesses including leukemia, lymphoma, HIV, and obesity.[1]
History
[edit]WuXi PharmaTech was founded in December 2000 in Shanghai by organic chemist Ge Li.[2][3] The company initially focused on chemistry services.[4][5]
In 2007, the company launched an initial public offering in the U.S. with shares traded on the New York Stock Exchange under the symbol "WX."[6] That year, it also opened chemistry facilities in Tianjin.[7]
In 2008, WuXi PharmaTech acquired AppTec Laboratory Services Inc., a US-based company founded in 2001 with expertise in medical-device and biologics testing and with facilities in St. Paul, MN; Philadelphia, PA; and Atlanta, GA. In the same year, the company was renamed WuXi AppTec.[8][9] WuXi AppTec opened a toxicology facility in Suzhou in 2009.[10]
WuXi AppTec's subsidiary, WuXi STA, opened a large-scale manufacturing facility in Jinshan in 2010. The company began a biologics discovery, development, and manufacturing operation in Shanghai and Wuxi City in 2011. At the same year, WuXi AppTec acquired MedKey, a China-based clinical research company,[11] and Abgent, a San Diego company and one of the world's largest manufacturers of antibodies for biological research and drug discovery.[12] In 2012, WuXi AppTec opened a chemistry facility in Wuhan and a GMP biologics drug-substance facility in Wuxi City. That year WuXi AppTec also entered into a joint venture with MedImmune, the biologics arm of AstraZeneca, to co-develop MEDI5117, an anti-IL6 antibody for rheumatoid arthritis for the Chinese market.[13] In 2013, WuXi AppTec formed a joint venture with the global clinical contract research organization PRA International (now called PRA Health Sciences) to build a clinical research business in China.[14]
In 2014, WuXi AppTec opened a new biologics biosafety testing facility in Suzhou. In the same year, WuXi AppTec acquired XenoBiotic Laboratories, Inc. (XBL), a contract research organization with 27 years of operation that provides bioanalytical, drug metabolism, and pharmacokinetic services to the pharmaceutical, animal health, and agrochemical industries.[15]
In 2015, WuXi AppTec and other Chinese firms delisted their stocks from U.S. exchanges in a bid to obtain higher valuations closer to home.[16] WuXi AppTec completed its merger with WuXi Merger Limited, a wholly owned subsidiary of New WuXi Life Science Limited. As a result of the merger, New WuXi Life Science Limited acquired the company in a cash transaction valued at approximately US$3.3 billion.[17] In 2016, WuXi STA opened a new campus in Changzhou[18] and operations in San Diego. In the same year, WuXi AppTec acquired Crelux GmbH, a structure-based drug discovery provider based in Munich, Germany.[19] In 2017, WuXi AppTec acquired HD Biosciences (HDB), a biology focused preclinical drug discovery contract research organization (CRO).[20]
In 2015, the company launched the subsidiary WuXi NextCODE following the acquisition of NextCODE Health, a bioinformatics startup company which emerged from the Icelandic firm deCODE genetics in 2013.[21] Later, in 2019, WuXi NextCODE separated from WuXi AppTec in response to new regulations in China, and became Genuity Science. This company was then acquired by the New York biotech firm HiberCell in August 2021.[22]
In 2017, WuXi AppTec's biologics division, WuXi Biologics, was spun off and listed on the Hong Kong Stock Exchange.[23] In 2018, WuXi AppTec itself completed an initial public offering in Shanghai, raising over $900 million, and then subsequently listed shares in Hong Kong for an initial valuation of $1 billion.[24][25]
In 2019, WuXi AppTec acquired Pharmapace, a U.S.-based biometrics and clinical data company.[26]
In 2020, WuXi STA opened a new oligonucleotide API plant in Changzhou.[27] The next year, the subsidiary acquired a tablet and capsule manufacturing plant in Switzerland from Bristol Myers Squibb.[28]
In 2021, WuXi AppTec acquired Oxgene, a UK-based cell and gene therapy firm.[29] In 2022, the firm announced plans to develop a manufacturing site in Middletown, Delaware, as well as a $1.4 billion facility expansion in Singapore.[30][31] The company also opened a high-potency API facility in Jiangsu, China.[32]
In January 2024, WuXi AppTec's share price fell on news that the United States Congress had introduced legislation called the Biosecure Act to block any federal government contracts with the company due to national security concerns.[33][34][35] The concerns stem from allegations, denied by the company, that it has worked closely with the People's Liberation Army (PLA) as a part of the Chinese Communist Party (CCP)'s military-civil fusion strategy.[36] On February 12, 2024, the chair and ranking member of the United States House Select Committee on Strategic Competition between the United States and the Chinese Communist Party joined Senators Gary Peters and Bill Hagerty in urging the Departments of the Treasury, Defense, and Commerce to review WuXi AppTec and WuXi Biologics for sanctions and to consider adding them to U.S. control lists.[37] WuXi AppTec denied any affiliation with the CCP and PLA and launched a lobbying campaign in the US in response.[38] On March 28, 2024, Reuters reported—citing two sources familiar with a classified briefing led by U.S. intelligence and diplomatic officials—that WuXi AppTec had transferred a U.S. client's intellectual property to Chinese authorities without consent; WuXi AppTec denied any unauthorized transfers and said it complies with U.S. law.[39]
In October 2024, WuXi AppTec was reportedly considering selling its facilities in the U.S. and Europe due to the Biosecure Act, which has been discouraging potential clients.[40] In December 2024, WuXi AppTec announced that it would sell its Oxford Genetics (Oxgene) and WuXi Advanced Therapies to a U.S.-based private equity firm.[41][42] In January 2025, the company divested its U.S. medical device testing operations, with locations in Minnesota and Georgia, to the medical device contract research organization NAMSA.[43] In October 2025, the United States Department of Defense stated that WuXi AppTec merits inclusion on a list of companies linked to China's military.[44]
The Biosecure Act failed in the 2024 session of Congress, but was re-introduced in 2025 as part of the National Defense Authorization Act for Fiscal Year 2026, and was signed into law on 18 December, 2025.[45] In June 2026 the Department of Defense included WuXi AppTec in its list "1260H list" of “Chinese military companies” operating in the US.[46][47]
Operations
[edit]WuXi AppTec provides a range of services, including drug discovery, development, and manufacturing for small molecules, peptides and more.[4][48] As of 2025, the company reported around 39,000 employees and 6,000 customers.[49] WuXi AppTec's global network includes 20 sites, with major hubs in China, the United States, Germany, Switzerland, and Singapore.[50][49] Clients have included Chinese drugmakers like Jiangsu Hengrui, along with American and European firms like GlaxoSmithKline, AstraZeneca and Pfizer.[51]
WuXi Apptec is listed on the Shanghai Stock Exchange and the Hong Kong Stock Exchange, and is a component of the Hang Seng Index.[52][53][54]
References
[edit]- ↑ Jewett, Christina (15 April 2024). "Chinese Company Under Congressional Scrutiny Makes Key U.S. Drugs". The New York Times. Retrieved 24 October 2025.
- ↑ "Company Profile/ leadership". WuXi AppTec. Archived from the original on 15 April 2021. Retrieved 29 March 2021.
- ↑ "Company Profile/ History". WuXi AppTec. Archived from the original on 15 April 2021. Retrieved 29 March 2021.
- 1 2 Tremblay, Jean-François; C, special to; EN (21 January 2025). "WuXi AppTec is C&EN's 2018 Company of the Year". Chemical & Engineering News. Retrieved 5 September 2025.
- ↑ Dyer, Geoff (18 October 2005). "China: Seeds are sown but few are harvested". The Financial Times. Retrieved 4 September 2025.
- ↑ "Form 424(b)(4)". www.sec.gov. Retrieved 5 September 2025.
- ↑ "Wuxi chemistry lab opens in Tianjin". Chemical & Engineering News. 21 January 2025. Retrieved 5 September 2025.
- ↑ "Our History". WuXi AppTec. Archived from the original on 22 December 2023. Retrieved 26 December 2023.
- ↑ Nagaraj, Amulya; Shen, Samuel (4 January 2008). "WuXi to acquire U.S.-based biopharmaceutical company". reuters.com. Archived from the original on 7 December 2023. Retrieved 3 January 2024.
- ↑ "Our History". WuXi AppTec. 29 March 2019. Archived from the original on 17 June 2020. Retrieved 24 June 2020.
- ↑ WuXi Acquires Chinese Clinical CROs MedKey and Jiecheng Archived 2022-06-26 at the Wayback Machine 24 October 2011 www.genengnews.com, accessed 28 March 2021
- ↑ WuXi PharmaTech Acquires Abgent, a Leading Producer of Biological Research Reagents Archived 2024-03-20 at the Wayback Machine 14 October 2011 www.fiercebiotech.com, accessed 28 March 2021
- ↑ MedImmune, WuXi form joint venture Archived 2024-03-20 at the Wayback Machine 10 September 2012 www.biospectrumasia.com, accessed 28 March 2021
- ↑ WuXi and PRA form Chinese joint venture Archived 2021-01-11 at the Wayback Machine 8 January 2013 www.pmlive.com, accessed 28 March 2021
- ↑ WuXi PharmaTech acquires XenoBiotic Labs Archived 2015-10-24 at the Wayback Machine 1 October 2014 www.thepharmaletter.com, accessed 28 March 2021
- ↑ Lane, E. J. (17 August 2015). "Going private for WuXi PharmaTech opens dealmaking options | Fierce Pharma". www.fiercepharma.com. Retrieved 5 September 2025.
- ↑ Conyers advises New WuXi Life Science Ltd. in connection with US$3.3 billion buyout Archived 2021-04-14 at the Wayback Machine www.conyers.com, accessed 29 March 2021
- ↑ WuXi AppTec's STA Subsidiary Opens New Campus In Changzhou Archived 2022-11-13 at the Wayback Machine 4 March 2016 www.biospace.com, accessed 29 March 2021
- ↑ WuXi Apptec acquire Crelux GmbH Archived 2024-03-20 at the Wayback Machine 19 April 2016 biopharma-asia.com, accessed 29 March 2021
- ↑ WuXi AppTec acquires HD Biosciences Archived 2021-01-22 at the Wayback Machine 20 January 2017 www.centerwatch.com, accessed 29 March 2021
- ↑ Fidler, Ben (23 October 2013). "DeCode Spinout, NextCode Health, Launches With $15M From Arch, Polaris". Xconomy. Boston. Archived from the original on 27 June 2020. Retrieved 24 June 2020.
- ↑ Vinluan, Frank (16 August 2021). "HiberCell's Genuity buyout brings $100M, plus alliances with Ionis and AbbVie". MedCity News. Retrieved 8 September 2025.
- ↑ "WuXi Biologics prices HK IPO at top as investors seek growth business". Reuters. 6 June 2017. Retrieved 8 September 2025.
- ↑ Liu, Angus (28 March 2018). "WuXi AppTec gets fast-track approval for $900M-plus Shanghai IPO | Fierce Biotech". www.fiercebiotech.com. Retrieved 8 September 2025.
- ↑ Chiu, Joanne (28 November 2018). "Chinese Drug Researcher Kicks Off $1 Billion Hong Kong Listing". Wall Street Journal. ISSN 0099-9660. Retrieved 8 September 2025.
- ↑ Adams, Ben (8 May 2019). "China's WuXi AppTec buys up U.S. Pharmapace, boosting biometrics offering | Fierce Biotech". www.fiercebiotech.com. Retrieved 9 September 2025.
- ↑ Mullin, Rick (21 January 2025). "WuXi's STA unit opens oligonucleotide plant". Chemical & Engineering News. Retrieved 9 September 2025.
- ↑ Kansteiner, Fraiser (2 February 2021). "Bristol Myers offloading Swiss tablet and capsule plant to Chinese CDMO WuXi STA | Fierce Pharma". www.fiercepharma.com. Retrieved 9 September 2025.
- ↑ Hargreaves, Ben (4 March 2021). "WuXi AppTec absorbs Oxgene to expand cell and gene services". BioProcess International. Retrieved 9 September 2025.
- ↑ Kostelni, Natalie (28 June 2021). "Delaware signs off on $19M in tax incentives for WuXi AppTec division's Project Dragonfly". www.bizjournals.com. Retrieved 9 September 2025.
- ↑ "Chinese Biotech Duo Eyes $2.8 Billion Singapore Expansion - Caixin Global". www.caixinglobal.com. Retrieved 9 September 2025.
- ↑ Keenan, Joseph (28 June 2022). "WuXi debuts another high-potency API production facility". www.fiercepharma.com. Retrieved 9 September 2025.
- ↑ "WuXi Bio Denies Military Ties After Shares Slumped on US Bill". Bloomberg News. 29 January 2024. Archived from the original on 29 January 2024. Retrieved 30 January 2024.
- ↑ Venkat, P.R.; Qin, Sherry (28 January 2024). "WuXi AppTec Shares Continue Slide After Company Calls U.S. Draft Bill Findings Inaccurate". The Wall Street Journal. Archived from the original on 29 January 2024. Retrieved 29 January 2024.
- ↑ "WuXi Company Shares Tumble on U.S. Bill Aimed at Chinese Biotech". The Wall Street Journal. 2 February 2024. Archived from the original on 1 February 2024. Retrieved 2 February 2024.
- ↑ Cheung, Sunny; Hope, Arran; Mattis, Peter (9 February 2024). "Red Genes: Assessing WuXi AppTec's Ties to the Party-Army-State in China". Jamestown Foundation. Archived from the original on 10 February 2024. Retrieved 11 February 2024.
- ↑ Martina, Michael (12 February 2024). "US lawmakers call for sanctions on China's WuXi AppTec biotech firm". Reuters. Retrieved 12 February 2024.
- ↑ Olcott, Eleanor; Wang, Xueqiao (19 March 2024). "Chinese pharma group lobbies against US biotech crackdown". Financial Times. Archived from the original on 19 March 2024. Retrieved 20 March 2024.
- ↑ "China's WuXi AppTec shared US client's data with Beijing, US intelligence officials told senators". Reuters. 28 March 2024. Retrieved 28 March 2024.
- ↑ Barnes, Oliver; Fontanella-Khan, James; Olcott, Eleanor (3 October 2024). "China's WuXi explores sale of pharma units as US restrictions loom". Financial Times. Retrieved 25 December 2024.
- ↑ "China's WuXi to sell Advanced Therapies unit amid US restrictions". Reuters. 24 December 2024. Retrieved 25 December 2024.
- ↑ Stanton, Dan. "WuXi AppTec selling CGT unit as BIOSECURE continues to play out". www.bioprocessintl.com. Retrieved 22 September 2025.
- ↑ "WuXi AppTec sees growth after 2024 dip, plans 'lean' operations to temper 'external opportunities'". Endpoints News. Retrieved 4 September 2025.
- ↑ Capaccio, Anthony (26 November 2025). "Pentagon Cited Alibaba on China Military Aid in Oct. 7 Letter". Bloomberg News. Retrieved 28 November 2025.
{{cite news}}: CS1 maint: deprecated archival service (link) - ↑ Christensen, Guillermo S.; Armstrong, Sheila A.; Gelbman, Scott J.; Tabler, Andrew H.; Hopkins, Brian J. (20 January 2026). "What You Need to Know About the Biosecure Act". The National Law Review. Retrieved 15 June 2026.
- ↑ Pratap, Aayushi (10 June 2026). "Pentagon ruling hits China's WuXi AppTec". Chemical & Engineering News. Retrieved 15 June 2026.
- ↑ Martina, Michael; Shepardson, David; Baptista, Eduardo (8 June 2026). "US says BYD, Baidu, Alibaba and other tech giants are aiding China's military". Reuters. Retrieved 10 June 2026.
- ↑ Haigney, Susan (9 January 2024). "WuXi AppTec Expands Peptide and API Manufacturing". BioPharm International. Retrieved 12 September 2025.
- 1 2 "2024 Annual Report" (PDF). Wuxiapptec.com. Retrieved 11 September 2025.
- ↑ Slabodkin, Greg (18 August 2025). "Q&A: WuXi AppTec's key investment focus is on expanding capabilities for new modalities". Pharma Manufacturing. Retrieved 13 September 2025.
- ↑ Dreyer, Jacob (17 August 2025). "China's Biotech Is Cheaper and Faster". The New York Times. Retrieved 12 September 2025.
- ↑ "603259.SS - | Stock Price & Latest News | Reuters". www.reuters.com. Retrieved 12 September 2025.
- ↑ "WuXi AppTec Co., LTD (2359.HK)". Yahoo! Finance. Retrieved 12 September 2025.
- ↑ "HSI Members - Hong Kong Hang Seng Index". Bloomberg.com. Archived from the original on 5 July 2017. Retrieved 12 September 2025.
- Companies in the SSE 50 Index
- Hang Seng China 50 Index
- Manufacturing companies based in Shanghai
- Pharmaceutical companies of China
- Companies formerly listed on the New York Stock Exchange
- Companies listed on the Shanghai Stock Exchange
- Companies listed on the Hong Kong Stock Exchange
- Companies in the FTSE China A50 Index
- Companies in the CSI 100 Index
- Pharmaceutical companies established in 2000
- Contract research organizations
- Multinational companies headquartered in China
- Life sciences industry
- Chinese brands
- Chinese companies established in 2000
- 2000 in Wuxi