// Workers AI · dad joke modeWhat did Regulating synaptic membrane exocytosis 3 say? It had a lot on its membrane.

RIMS3
Identifiers
Aliases	RIMS3, NIM3, RIM3, regulating synaptic membrane exocytosis 3, RIM 3
External IDs	OMIM: 611600; MGI: 2443331; GeneCards: RIMS3
Gene location (Human)
Chr.	Chromosome 1 (human)
End	40,665,682 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,753,776 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; Brodmann area 46; ; superior frontal gyrus; ; orbitofrontal cortex; ; Brodmann area 10; ; frontal pole; ; postcentral gyrus; ; primary visual cortex;
	Top expressed in
	medial dorsal nucleus; ; medial geniculate nucleus; ; superior colliculus; ; lateral geniculate nucleus; ; dorsomedial hypothalamic nucleus; ; paraventricular nucleus of hypothalamus; ; suprachiasmatic nucleus; ; ventral tegmental area; ; lateral hypothalamus; ; inferior colliculi;
	More reference expression data
	n/a
Gene ontology
Molecular function	transmembrane transporter binding;
Cellular component	presynaptic active zone; cell junction; synapse; membrane; presynaptic membrane; cytoskeleton of presynaptic active zone; presynaptic active zone cytoplasmic component;
Biological process	neurotransmitter transport; calcium-ion regulated exocytosis; exocytosis; regulation of membrane potential; calcium ion-regulated exocytosis of neurotransmitter; regulation of synaptic vesicle exocytosis; regulation of synaptic plasticity; positive regulation of synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	9783
	242662
	ENSG00000117016
	ENSMUSG00000032890
	Q9UJD0
	Q80U57
	NM_014747
	NM_182929
	NP_055562
	NP_891559
	Wikidata
View/Edit Human	View/Edit Mouse

Regulating synaptic membrane exocytosis 3 is a protein that in humans is encoded by the RIMS3 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000117016 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032890 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Regulating synaptic membrane exocytosis 3". Archived from the original on 2020-09-22. Retrieved 2018-06-13.

Weidenhofer J, Scott RJ, Tooney PA (January 2009). "Investigation of the expression of genes affecting cytomatrix active zone function in the amygdala in schizophrenia: effects of antipsychotic drugs". J Psychiatr Res. 43 (3): 282–90. doi:10.1016/j.jpsychires.2008.04.001. PMID 18490030.
Kumar RA, Sudi J, Babatz TD, Brune CW, Oswald D, Yen M, Nowak NJ, Cook EH, Christian SL, Dobyns WB (February 2010). "A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism". J. Med. Genet. 47 (2): 81–90. doi:10.1136/jmg.2008.065821. PMC 2921284. PMID 19546099.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000117016 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032890 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Regulating synaptic membrane exocytosis 3". Archived from the original on 2020-09-22. Retrieved 2018-06-13.

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References

Further reading