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// Workers AI · dad joke modeWhat did Florpyrauxifen-benzyl say? "I'm a growing concern.

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Florpyrauxifen-benzyl
Names
IUPAC name
Benzyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylate
Other names
ProcellaCOR
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.249.071 Edit this at Wikidata
EC Number
  • 815-125-3
UNII
  • InChI=1S/C20H14Cl2F2N2O3/c1-28-19-12(21)8-7-11(14(19)23)17-15(24)16(25)13(22)18(26-17)20(27)29-9-10-5-3-2-4-6-10/h2-8H,9H2,1H3,(H2,25,26)
    Key: WNZCDFOXYNRBRB-UHFFFAOYSA-N
  • COC1=C(C=CC(=C1F)C2=NC(=C(C(=C2F)N)Cl)C(=O)OCC3=CC=CC=C3)Cl
Properties
C20H14Cl2F2N2O3
Molar mass 439.24 g·mol−1
Hazards
GHS labelling:
GHS07: Exclamation markGHS09: Environmental hazard
Warning
H317, H410
P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Florpyrauxifen-benzyl is an aquatic herbicide used to manage invasive aquatic plants such as Myriophyllum spicatum (Eurasian watermilfoil). It was assessed by the EPA in 2017[1] and then registered by the EPA in 2018.[2] It was registered by the Health Canada Pest Management Regulatory Agency in 2023.[3] It is the active ingredient in herbicidal products such as ProcellaCOR.

In the fall of 2024, Farlain Lake, Ontario, was the first freshwater Canadian lake to be treated with ProcellaCOR.[4]

In June 2024, Minnesota Department of Agriculture listed florpyrauxifen-benzyl as meeting the definition of a PFAS.[5][6] However, the Chautauqua Lake Partnership quotes the New York State Department of Environmental Conservation as stating:

"New York State approved its registration in 2019. EPA’s review of current federally registered pesticides found 'no pesticide active or inert ingredients with structures similar to prominent PFAS such as PFOS, PFOA, and GenX.'"[7][8]

In June 2024,[9] ProcellaCOR was used to treat two sites on Lake George, New York. Testing in 2025 found that it was effective in managing the targeted plants while having negligible impact on native plants. The testing found the expected degradants from ProcellaCOR along with detectable amounts of its active ingredient (florpyrauxifen-benzyl) in core samples 15 to 20 cm deep.[10]

In March, 2025, it was reported that the Okanagan Water Basin Board, located in the Okanagan Valley, British Columbia, was against the application of ProcellaCOR and that the Okanagan Nation Alliance supported their position.[11]

References

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  1. ↑ Meléndez, José; Vogel, Van; Sappington, Keith. Florpyrauxifen-benzyl Environmental Fate and Ecological Risk Assessment for the Section 3 New Chemical Registration. EPA (Technical report). EPA-HQ-OPP-2016-0560-0011. Retrieved March 24, 2026.
  2. ↑ "EPA Reg. No. 67690-79" (PDF). EPA. Retrieved March 24, 2026.
  3. ↑ "Registration Decision RD2023-08, Florpyrauxifen-benzyl, Milestone NXT Herbicide, Restore NXT Herbicide, GF-3206 Herbicide, GF-3301 Aquatic Herbicide, and ProcellaCOR FX Herbicide". Health Canada. May 16, 2023. Retrieved March 23, 2025.
  4. ↑ "Invasive plant 'appears' to be eradicated from area lake". Barrie Today. Barrie, Ontario. September 24, 2024. Retrieved March 24, 2026.
  5. ↑ "Pesticide Active and Inert Ingredients Categorized as PFAS". Minnesota Department of Agriculture. Retrieved March 24, 2026.
  6. ↑ Portal, Alex (May 23, 2024). "PFAS Enters the Lake George, ProcellaCOR Debate". The Post-Star. Glens Falls, New York. pp. A1, A3.
  7. ↑ "CLA Erroneous Allegations Regarding Herbicide ProcellaCOR". Chautauqua Lake Partnership. June 12, 2024. Retrieved March 24, 2026.
  8. ↑ "Per- and Polyfluoroalkyl Substances (PFAS) in Pesticide and Other Packaging". EPA. January 13, 2021. Retrieved March 24, 2026. Interestingly, there are reports of PFAS from pesticides shipped in an HDPE container.
  9. ↑ Portal, Alex (June 30, 2024). "It's in the Lake: ProcellaCOR Applied to the Waters of Lake George". The Post-Star. Glens Falls, New York. pp. A1, A2.
  10. ↑ Portal, Alex (October 11, 2025). "A Deeper Dive into the LGA's ProcellaCOR Report". The Post-Star. Glens Falls, New York. pp. A1, A6.
  11. ↑ "Water briefs: Staff changes for Okanagan Basin Water Board". West K News. Kelowna, British Columbia. March 7, 2025. Retrieved March 26, 2026.
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