// Workers AI · dad joke modeWhy was Calpain-8 sad? It was cut up about something.

CAPN8
Identifiers
Aliases	CAPN8, nCL-2, calpain 8
External IDs	MGI: 2181366; HomoloGene: 15643; GeneCards: CAPN8; OMA:CAPN8 - orthologs
Enzyme activity
Gene location (Human)
Chr.	Chromosome 1 (human)
End	223,665,723 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	182,459,917 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; mucosa of ileum; ; pylorus; ; gastric mucosa; ; pancreatic ductal cell; ; rectum; ; upper lobe of left lung; ; body of stomach; ; gallbladder; ; mucosa of sigmoid colon;
	Top expressed in
	pyloric antrum; ; epithelium of stomach; ; mucous cell of stomach; ; hair follicle; ; lip; ; embryo; ; embryo; ; duodenum; ; skin of abdomen; ; left colon;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; hydrolase activity; cysteine-type peptidase activity; metal ion binding; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity;
Cellular component	Golgi apparatus; intracellular anatomical structure; cytoplasm;
Biological process	proteolysis; digestion;
	Sources:Amigo / QuickGO
Orthologs
	388743
	170725
	ENSG00000203697
	ENSMUSG00000038599
	A6NHC0; A3QK37
	Q91VA3
	NM_001143962
	NM_001145806; NM_130890
	NP_001137434
	NP_001139278; NP_570960
	Wikidata
View/Edit Human	View/Edit Mouse

Calpain-8 is a protein in humans that is encoded by the CAPN8 gene.^[5] ^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000203697 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038599 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "CAPN8 - Calpain-8 - Homo sapiens (Human) - CAPN8 gene & protein". www.uniprot.org. Retrieved 18 May 2022.
↑ "Entrez Gene: Calpain 8". Retrieved 2012-12-16.