Solute carrier family 22 member 15

SLC22A15
Identifiers
Aliases	SLC22A15, FLIPT1, PRO34686, solute carrier family 22 member 15
External IDs	OMIM: 608275; MGI: 3607704; GeneCards: SLC22A15
Gene location (Human) Chr. Chromosome 1 (human) Band 1p13.1 Start 115,976,498 bp End 116,070,054 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 F2.2 Start 101,855,776 bp End 101,924,453 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum monocyte inferior ganglion of vagus nerve bone marrow C1 segment subthalamic nucleus Brodmann area 46 trabecular bone bone marrow cell right lung Top expressed in granulocyte spermatid spermatocyte epithelium of lens substantia nigra trigeminal ganglion urethra genital tubercle Paneth cell lip More reference expression data BioGPS n/a
Gene ontology Molecular function transmembrane transporter activity organic anion transmembrane transporter activity Cellular component integral component of membrane membrane Biological process ion transport transmembrane transport organic anion transport Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 55356 242126 Ensembl ENSG00000163393 ENSMUSG00000033147 UniProt Q8IZD6 Q504N2 RefSeq (mRNA) NM_018420 NM_001039371 RefSeq (protein) NP_060890 NP_001034460 Location (UCSC) Chr 1: 115.98 – 116.07 Mb Chr 3: 101.86 – 101.92 Mb PubMed search
Wikidata
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Solute carrier family 22 member 15 is a protein that in humans is encoded by the SLC22A15 gene.

Function

Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.