Peroxiredoxin-like 2A

PRXL2A
Identifiers
Aliases	PRXL2A, C10orf58, PAMM, family with sequence similarity 213 member A, Adrx, FAM213A, peroxiredoxin like 2A
External IDs	OMIM: 617165; MGI: 1917814; HomoloGene: 12356; GeneCards: PRXL2A; OMA:PRXL2A - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	80,437,115 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	40,735,745 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; corpus epididymis; ; myocardium of left ventricle; ; skin of thigh; ; mucosa of ileum; ; jejunal mucosa; ; skin of arm; ; caput epididymis; ; skin of hip; ; vulva;
	Top expressed in
	retinal pigment epithelium; ; blood; ; utricle; ; tunica adventitia of aorta; ; ciliary body; ; brown adipose tissue; ; Epithelium of choroid plexus; ; white adipose tissue; ; vestibular sensory epithelium; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	antioxidant activity;
Cellular component	cytoplasm; extracellular region;
Biological process	regulation of osteoclast differentiation; cellular oxidant detoxification;
	Sources:Amigo / QuickGO
Orthologs
	84293
	70564
	ENSG00000122378
	ENSMUSG00000021792
	Q9BRX8
	Q9CYH2
NM_001243778; NM_001243779; NM_001243780; NM_001243781; NM_001243782;
	NM_032333
NM_027464; NM_001316732; NM_001316733; NM_001316734; NM_001316735;
	NM_001316736; NM_001316737; NM_001316739; NM_001316740; NM_001378813; NM_001378814; NM_001378815
NP_001230707; NP_001230708; NP_001230709; NP_001230710; NP_001230711;
	NP_115709
NP_001303661; NP_001303662; NP_001303663; NP_001303664; NP_001303665;
	NP_001303666; NP_001303668; NP_001303669; NP_081740; NP_001365742; NP_001365743; NP_001365744
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxiredoxin-like 2A is a protein that in humans is encoded by the PRXL2A gene.^[5]^[6] PRXL2A is also known as redox-regulatory protein FAM213A and peroxiredoxin-like 2 activated in M-CSF stimulated monocytes (PAMM).

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122378 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021792 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
↑ "Entrez Gene: C10orf58 chromosome 10 open reading frame 58".

Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–126. doi:10.1093/dnares/12.2.117. PMID 16303743.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000122378 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021792 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11483580-5] Yu Y, Zhang C, Zhou G, Wu S, Qu X, Wei H, Xing G, Dong C, Zhai Y, Wan J, Ouyang S, Li L, Zhang S, Zhou K, Zhang Y, Wu C, He F (Aug 2001). "Gene expression profiling in human fetal liver and identification of tissue- and developmental-stage-specific genes through compiled expression profiles and efficient cloning of full-length cDNAs". Genome Res. 11 (8): 1392–1403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.

[entrez-6] "Entrez Gene: C10orf58 chromosome 10 open reading frame 58".

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Peroxiredoxin-like 2A

References

Further reading