// Workers AI · dad joke modeWhy was Pleckstrin homology and RhoGEF domain containing G3 sad? It had a cell-ebration to attend.

PLEKHG3
Identifiers
Aliases	PLEKHG3, ARHGEF43, KIAA0599, pleckstrin homology and RhoGEF domain containing G3
External IDs	OMIM: 617940; MGI: 2388284; GeneCards: PLEKHG3
Gene location (Human)
Chr.	Chromosome 14 (human)
End	64,750,249 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	76,627,262 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; popliteal artery; ; tibial arteries; ; right coronary artery; ; corpus callosum; ; granulocyte; ; body of uterus; ; C1 segment; ; left uterine tube; ; left coronary artery;
	Top expressed in
	ascending aorta; ; granulocyte; ; zygote; ; aortic valve; ; primary oocyte; ; molar; ; secondary oocyte; ; tail of embryo; ; lip; ; gastrula;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	26030
	263406
	ENSG00000126822
	ENSMUSG00000052609
	A1L390
	Q4VAC9
	NM_001308147; NM_015549
	NM_153804
	NP_001295076
	NP_722499; NP_001390126; NP_001390127
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin homology and RhoGEF domain containing G3 is a protein that in humans is encoded by the PLEKHG3 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000126822 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000052609 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Pleckstrin homology and RhoGEF domain containing G3". Retrieved 2018-05-29.

Griswold AJ, Ma D, Sacharow SJ, Robinson JL, Jaworski JM, Wright HH, Abramson RK, Lybaek H, Øyen N, Cuccaro ML, Gilbert JR, Pericak-Vance MA (June 2011). "A de novo 1.5 Mb microdeletion on chromosome 14q23.2-23.3 in a patient with autism and spherocytosis". Autism Res. 4 (3): 221–7. doi:10.1002/aur.186. PMC 3110642. PMID 21360829.

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