Peroxin-7

peroxisomal biogenesis factor 7
peroxisomal biogenesis factor 7
Identifiers
Symbol	PEX7
NCBI gene	5191
HGNC	8860
OMIM	601757
RefSeq	NM_000288
UniProt	O00628
Other data
Locus	Chr. 6 q21-q22.2
Structures
Search for
Structures	Swiss-model
Domains	InterPro

PEX7
Identifiers
Aliases	PEX7, PBD9B, PTS2R, RCDP1, RD, peroxisomal biogenesis factor 7
External IDs	OMIM: 601757; MGI: 1321392; HomoloGene: 242; GeneCards: PEX7; OMA:PEX7 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	136,913,934 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	19,783,435 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; sperm; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; secondary oocyte; ; gonad; ; body of pancreas; ; left adrenal cortex; ; kidney tubule;
	Top expressed in
	left lobe of liver; ; right kidney; ; right ventricle; ; triceps brachii muscle; ; spermatocyte; ; proximal tubule; ; sternocleidomastoid muscle; ; epithelium of stomach; ; pyloric antrum; ; brown adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	enzyme binding; peroxisome matrix targeting signal-2 binding; protein homodimerization activity;
Cellular component	cytoplasm; peroxisome; peroxisomal matrix; peroxisomal membrane; cytosol;
Biological process	protein transport; fatty acid beta-oxidation; peroxisome organization; neuron migration; protein import into peroxisome matrix; endochondral ossification; ether lipid biosynthetic process; protein targeting to peroxisome;
	Sources:Amigo / QuickGO
Orthologs
	5191
	18634
	ENSG00000112357
	ENSMUSG00000020003
	O00628
	P97865
	NM_000288
	NM_001161825; NM_008822
	NP_000279
	NP_001155297; NP_032848
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxin-7 is a receptor associated with Refsum's disease and rhizomelic chondrodysplasia punctata type 1. Peroxin-7 is encoded in humans by the PEX7 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000112357 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020003 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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