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// Workers AI · dad joke modeWhy did P4 go to therapy? It had a phage-ing issue.

From Wikipedia, the free encyclopedia
(Redirected from P4 phage)
Enterobacteria phage P4
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Uroviricota
Class: Caudoviricetes
Family: Peduoviridae
Genus: Peduovirus
Species:
Strain:
Enterobacteria phage P4

Enterobacteria phage P4 (also known as satellite phage P4) is a temperate bacteriophage strain of species Escherichia virus P2 within genus Peduovirus (formerly P2-like viruses, P2virus, and P2likevirus), subfamily Peduovirinae, family Myoviridae.[1] It is a satellite virus, requiring P2-related helper phage to grow lytically.

Structure

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The P4 virion has a tail and an icosahedral head containing a linear double-stranded DNA genome of 11,627 kb.[2][3]

Life cycle

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Phage P4 infects Escherichia coli. It is a satellite virus which cannot engage in lytic growth without the presence of a P2-related helper phage. It generally follows a lysogenic life cycle: after infection, the P4 genome integrates into that of its host. The P4 genome can also exist on its own within the host cell and can replicate as a free plasmid.[4]

References

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  1. Pruss, G; Goldstein, RN; Calendar, R (June 1974). "In vitro packaging of satellite phage P4 DNA". Proceedings of the National Academy of Sciences of the United States of America. 71 (6): 2367–71. Bibcode:1974PNAS...71.2367P. doi:10.1073/pnas.71.6.2367. PMC 388456. PMID 4526304.
  2. Briani, Federica; Dehò, Gianni; Forti, Francesca; Ghisotti, Daniela (2002). "The Plasmid Status of Satellite Bacteriophage P4". Plasmid. 45 (1): 1–17. doi:10.1006/plas.2000.1497. PMID 11319927.
  3. Claverie JM, Abergel C (2009). "Mimivirus and its Virophage". Annual Review of Genetics. 43: 49–66. doi:10.1146/annurev-genet-102108-134255. PMID 19653859.
  4. Christie, GE; Calendar, R (1990). "Interactions between satellite bacteriophage P4 and its helpers". Annual Review of Genetics. 24: 465–90. doi:10.1146/annurev.ge.24.120190.002341. PMID 2088176.
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