// Workers AI · dad joke modeWhat did BTBD14B say to its date? Byte-ing to know you.

NACC1
Identifiers
Aliases	NACC1, BEND8, BTBD14B, BTBD30, NAC-1, NAC1, nucleus accumbens associated 1, NECFM
External IDs	OMIM: 610672; MGI: 1914080; GeneCards: NACC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GA1, 4U2N
Gene location (Human)
Chr.	Chromosome 19 (human)
End	13,141,147 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	85,414,531 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; nasal epithelium; ; skin of arm; ; stromal cell of endometrium; ; myocardium of left ventricle; ; prefrontal cortex; ; amygdala; ; anterior cingulate cortex; ; buccal mucosa cell; ; decidua;
	Top expressed in
	tail of embryo; ; genital tubercle; ; epiblast; ; zygote; ; ventricular zone; ; pyloric antrum; ; yolk sac; ; dentate gyrus of hippocampal formation granule cell; ; crypt of lieberkuhn of small intestine; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Orthologs
Databases	NCBI: entry; OMA: entry
	112939
	66830
	ENSG00000160877
	ENSMUSG00000001910
	Q96RE7
	Q7TSZ8
	NM_052876
	NM_025788
	NP_443108
	NP_080064
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleus accumbens-associated protein 1 is a protein that in humans is encoded by the NACC1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000160877 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001910 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Strausberg RL, Feingold EA, Grouse LH, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
↑ "Entrez Gene: BTBD14B BTB (POZ) domain containing 14B".

External links

Human NACC1 genome location and NACC1 gene details page in the UCSC Genome Browser.
PDBe-KB provides an overview of all the structure information available in the PDB for Human Nucleus accumbens-associated protein 1 (BTBD14B)

Nakayama K, Nakayama N, Wang TL, Shih IeM (2007). "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor". Cancer Res. 67 (17): 8058–64. doi:10.1158/0008-5472.CAN-07-1357. PMID 17804717.
Davidson B, Berner A, Trope' CG, et al. (2007). "Expression and clinical role of the bric-a-brac tramtrack broad complex/poxvirus and zinc protein NAC-1 in ovarian carcinoma effusions". Hum. Pathol. 38 (7): 1030–6. doi:10.1016/j.humpath.2006.12.009. PMID 17391728.
Nakayama K, Nakayama N, Davidson B, et al. (2007). "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival". Proc. Natl. Acad. Sci. U.S.A. 103 (49): 18739–44. doi:10.1073/pnas.0604083103. PMC 1693732. PMID 17130457.
Korutla L, Wang PJ, Mackler SA (2005). "The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures". J. Neurochem. 94 (3): 786–93. doi:10.1111/j.1471-4159.2005.03206.x. PMID 16033423. S2CID 42787411.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Korutla L, Wang PJ, Lewis DM, et al. (2002). "Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1". Neuroscience. 110 (3): 421–9. doi:10.1016/S0306-4522(01)00518-8. PMID 11906783. S2CID 13388723.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000160877 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001910 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: BTBD14B BTB (POZ) domain containing 14B".

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References

External links

Further reading