Major facilitator superfamily domain containing 2B

MFSD2B
Identifiers
Aliases	MFSD2B, major facilitator superfamily domain containing 2B, SLC59A2
External IDs	OMIM: 617845; MGI: 3583946; GeneCards: MFSD2B
Gene location (Human)
Chr.	Chromosome 2 (human)
End	24,063,321 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	4,924,359 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; bone marrow; ; testicle; ; bone marrow cell; ; thymus; ; gonad; ; stromal cell of endometrium; ; placenta; ; granulocyte;
	Top expressed in
	blood; ; spleen; ; yolk sac; ; bone marrow; ; neural layer of retina; ; embryo; ; human fetus; ; granulocyte; ; body of femur; ; blastocyst;
	More reference expression data
	n/a
Gene ontology
Molecular function	sphingolipid transporter activity; symporter activity; transporter activity;
Cellular component	membrane; integral component of membrane; plasma membrane; integral component of plasma membrane;
Biological process	lipid transport; carbohydrate transport; transmembrane transport; organic substance transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	388931
	432628
	ENSG00000205639
	ENSMUSG00000037336
	A6NFX1
	Q3T9M1
	NM_001080473; NM_001346880
	NM_001033488
	NP_001333809
	NP_001028660
	Wikidata
View/Edit Human	View/Edit Mouse

Major facilitator superfamily domain containing 2B is a protein that in humans is encoded by the MFSD2B gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000205639 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037336 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Major facilitator superfamily domain containing 2B". Retrieved 2018-09-28.

Angers M, Uldry M, Kong D, Gimble JM, Jetten AM (December 2008). "Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis". Biochem. J. 416 (3): 347–55. doi:10.1042/BJ20080165. PMC 2587516. PMID 18694395.
Bao L, Zhang Y, Wang J, Wang H, Dong N, Su X, Xu M, Wang X (October 2016). "Variations of chromosome 2 gene expressions among patients with lung cancer or non-cancer". Cell Biol. Toxicol. 32 (5): 419–35. doi:10.1007/s10565-016-9343-z. PMID 27301951. S2CID 17611299.

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