// Workers AI · dad joke modeDoes Leucine rich repeat go to parties? It has a repeat performance.

LRFN4
Identifiers
Aliases	LRFN4, FIGLER6, SALM3, SALM3., leucine rich repeat and fibronectin type III domain containing 4
External IDs	OMIM: 612810; MGI: 2385612; GeneCards: LRFN4
Gene location (Human) Chr. Chromosome 11 (human) Band 11q13.2 Start 66,856,647 bp End 66,860,475 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 A Start 4,661,813 bp End 4,665,695 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence right hemisphere of cerebellum mucosa of transverse colon apex of heart right frontal lobe anterior cingulate cortex right uterine tube stromal cell of endometrium decidua amygdala Top expressed in ventricular zone epiblast hand ganglionic eminence yolk sac superior frontal gyrus primary visual cortex external carotid artery dentate gyrus of hippocampal formation granule cell internal carotid artery More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cell surface membrane integral component of membrane plasma membrane extracellular space glutamatergic synapse GABA-ergic synapse integral component of postsynaptic density membrane Biological process axonogenesis regulation of postsynaptic density assembly synaptic membrane adhesion regulation of presynapse assembly Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 78999 225875 Ensembl ENSG00000173621 ENSMUSG00000045045 UniProt Q6PJG9 Q80XU8 RefSeq (mRNA) NM_024036 NM_001363524 NM_153388 RefSeq (protein) NP_076941 NP_001350453 NP_076941.2 NP_700437 Location (UCSC) Chr 11: 66.86 – 66.86 Mb Chr 19: 4.66 – 4.67 Mb PubMed search
Wikidata
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Leucine rich repeat and fibronectin type III domain containing 4 is a protein that in humans is encoded by the LRFN4 gene.

See also

• Fibronectin type III domain
• Leucine rich repeat

Further reading

• Konakahara S, Saitou M, Hori S, Nakane T, Murai K, Itoh R, Shinsaka A, Kohroki J, Kawakami T, Kajikawa M, Masuho Y (2011). "A neuronal transmembrane protein LRFN4 induces monocyte/macrophage migration via actin cytoskeleton reorganization". FEBS Lett. 585 (14): 2377–84. Bibcode:2011FEBSL.585.2377K. doi:10.1016/j.febslet.2011.06.011. PMID 21704618. S2CID 45719253.