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Lipase maturation factor 1 is an enzyme that in humans is encoded by the LMF1gene.[5][6][7] This protein is involved in the maturation and transport of lipoprotein lipase.[8] Pathogenic variants in this gene have been associated with a disorder called Combined Lipase Deficiency, which involves reduced lipoprotein lipase and hepatic lipase activity leading to excessive accumulation of fat and chylomicrons in the blood.[9]
↑Peterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH (Nov 2007). "Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia". Nat Genet. 39 (12): 1483–1487. doi:10.1038/ng.2007.24. PMID17994020. S2CID22277452.
Yamada S, Ohira M, Horie H, etal. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–5911. doi:10.1038/sj.onc.1207782. PMID15221005. S2CID3114318.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal. (1997). "Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library". Gene. 200 (1–2): 149–156. doi:10.1016/S0378-1119(97)00411-3. PMID9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–174. doi:10.1016/0378-1119(94)90802-8. PMID8125298.
