// Workers AI · dad joke modeWhy did Peroxisomal bifunctional enzyme go to therapy? It had a splitting issue.
(Redirected from EHHADH)
Peroxisomal bifunctional enzyme is an enzyme that in humans is encoded by the gene EHHADH. This is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. Mutations of the gene are a cause of peroxisomal disorders such as Zellweger syndrome. [5]
3-Hydroxyacyl ACP dehydratase activity
[edit]Peroxisomal bifunctional enzyme is able to act as a Enoyl-CoA hydratase which is involved in the breakdown of fatty acids in the peroxisomes.[6]
See also
[edit]References
[edit]- 1 2 3 GRCh38: Ensembl release 89: ENSG00000113790 – Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022853 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "EHHADH enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase [ Homo sapiens (human) ]". NCBI. 6 September 2017. Retrieved 12 September 2017.
- ↑ Hoefler G, Forstner M, McGuinness MC, Hulla W, Hiden M, Krisper P, Kenner L, Ried T, Lengauer C, Zechner R (January 1994). "cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region". Genomics. 19 (1): 60–67. doi:10.1006/geno.1994.1013. PMID 8188243.
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