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// Workers AI · dad joke modeWhat did dolichyl β-D-glucosyl phosphate say? I'm bonded to my work.

From Wikipedia, the free encyclopedia
(Redirected from Dol-P-glucose)
Dolichyl β-d-glucosyl phosphate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
  • InChI=1S/C31H55O9P/c1-22(2)11-7-12-23(3)13-8-14-24(4)15-9-16-25(5)17-10-18-26(6)19-20-38-41(36,37)40-31-30(35)29(34)28(33)27(21-32)39-31/h11,13,15,17,26-35H,7-10,12,14,16,18-21H2,1-6H3,(H,36,37)/b23-13+,24-15+,25-17-/t26?,27-,28-,29+,30-,31+/m1/s1
    Key: AGLXCEGQRIYVRV-DVDHLLHCSA-N
  • CC(CC/C=C(/C)\CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)CCOP(=O)(O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Properties
C26+5nH47+8nO9P
Molar mass variable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dolichyl β-d-glucosyl phosphate is a molecule involved in glycosylation. It is a polyprenyl glycosyl phosphate having dolichol as the polyprenyl component and β-d-glucose as the glycosyl component.[1][2]

Biosynthesis

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Dolichyl-phosphate beta-glucosyltransferase is an enzyme found in liver and calf pancreas that converts dolichol monophosphate to its glucoside. The glucose unit is transferred from UDP-glucose with uridine diphosphate (UDP) as byproduct.[3][4][5]

See also

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References

[edit]
  1. ↑ "Dolichyl b-D-glucosyl phosphate". PubChem. National Library of Medicine. Archived from the original on 2022-08-30. Retrieved 2022-08-30.
  2. ↑ Thiele, Ines; Swainston, Neil; Fleming, Ronan M. T.; Hoppe, Andreas; Sahoo, Swagatika; Aurich, Maike K.; Haraldsdottir, Hulda; Mo, Monica L.; Rolfsson, Ottar; Stobbe, Miranda D.; Thorleifsson, Stefan G.; Agren, Rasmus; Bölling, Christian; Bordel, Sergio; Chavali, Arvind K. (2013-05-12). "A community-driven global reconstruction of human metabolism". Nature Biotechnology. 31 (5): 419–425. doi:10.1038/nbt.2488. ISSN 1546-1696. PMC 3856361. PMID 23455439. S2CID 18461025.
  3. ↑ Behrens NH, Leloir LF (1970). "Dolichol monophosphate glucose: an intermediate in glucose transfer in liver". Proc. Natl. Acad. Sci. U.S.A. 66 (1): 153–9. Bibcode:1970PNAS...66..153B. doi:10.1073/pnas.66.1.153. PMC 286101. PMID 5273893.
  4. ↑ Herscovics A, Bugge B, Jeanloz RW (1977). "Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose". J. Biol. Chem. 252 (7): 2271–7. doi:10.1016/S0021-9258(17)40550-3. PMID 849929.
  5. ↑ Villemez CL, Carlo PL (1979). "Properties of a soluble polyprenyl phosphate: UDP-D-glucose glucosyltransferase". J. Biol. Chem. 254 (11): 4814–9. doi:10.1016/S0021-9258(17)30085-6. PMID 438216.


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