XTP3-transactivated gene A protein

DCTPP1
Identifiers
Aliases	DCTPP1, RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
External IDs	OMIM: 615840; MGI: 1913672; HomoloGene: 11329; GeneCards: DCTPP1; OMA:DCTPP1 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2A3Q, 2OIE, 2OIG, 2Q4P
Enzyme activity
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,430,030 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,859,881 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; parotid gland; ; oocyte; ; gonad; ; mucosa of sigmoid colon; ; endothelial cell; ; nasal epithelium; ; hair follicle; ; pancreatic ductal cell;
	Top expressed in
	embryo; ; embryo; ; epiblast; ; yolk sac; ; otic placode; ; primitive streak; ; somite; ; ventricular zone; ; medial ganglionic eminence; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; pyrophosphatase activity; protein binding; hydrolase activity; magnesium ion binding; metal ion binding; identical protein binding; pyrimidine deoxyribonucleotide binding; dCTP diphosphatase activity; nucleoside-triphosphate diphosphatase activity;
Cellular component	cytoplasm; cytosol; nucleus; mitochondrion;
Biological process	protein homotetramerization; dCTP catabolic process; nucleoside triphosphate catabolic process; DNA protection; dTTP catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	79077
	66422
	ENSG00000179958
	ENSMUSG00000042462
	Q9H773
	Q9QY93
	NM_024096
	NM_023203
	NP_077001
	NP_075692
	Wikidata
View/Edit Human	View/Edit Mouse

dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000179958 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042462 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.
↑ "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000179958 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042462 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15740738-5] Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.

[entrez-6] "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

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XTP3-transactivated gene A protein

See also

References

Further reading