Catenin alpha-2

CTNNA2
Identifiers
Aliases	CTNNA2, CAP-R, CAPR, CT114, CTNR, catenin alpha 2, CDCBM9
External IDs	OMIM: 114025; MGI: 88275; GeneCards: CTNNA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4K1O, 4ONS, 4P9T
Gene location (Human)
Chr.	Chromosome 2 (human)
End	80,648,861 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	77,956,682 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 46; ; superior frontal gyrus; ; postcentral gyrus; ; lateral nuclear group of thalamus; ; Brodmann area 10; ; corpus epididymis; ; dorsolateral prefrontal cortex; ; orbitofrontal cortex; ; sperm;
	Top expressed in
	ganglionic eminence; ; left lung; ; dermis; ; dentate gyrus of hippocampal formation granule cell; ; muscle of anterior abdominal wall; ; neural tube; ; superior frontal gyrus; ; lens; ; inferior colliculi; ; superior colliculus;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural molecule activity; actin filament binding; structural constituent of cytoskeleton; protein binding; cadherin binding; identical protein binding;
Cellular component	cytoplasm; cytosol; cell projection; membrane; adherens junction; plasma membrane; axon; cell junction; basolateral plasma membrane; actin cytoskeleton; cytoskeleton; nucleus; lamellipodium; postsynaptic density; hippocampal mossy fiber to CA3 synapse; parallel fiber to Purkinje cell synapse; presynaptic active zone cytoplasmic component; extrinsic component of presynaptic membrane; extrinsic component of postsynaptic membrane; postsynaptic density, intracellular component;
Biological process	cell differentiation; regulation of synapse structural plasticity; axonogenesis; dendrite morphogenesis; positive regulation of muscle cell differentiation; multicellular organism development; cell adhesion; radial glia guided migration of Purkinje cell; brain morphogenesis; prepulse inhibition; cytoskeleton organization; cell-cell adhesion; modification of postsynaptic actin cytoskeleton; regulation of neuron projection development; negative regulation of Arp2/3 complex-mediated actin nucleation; regulation of neuron migration;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	1496
	12386
	ENSG00000066032
	ENSMUSG00000063063
	P26232
	Q61301
NM_001164883; NM_001282597; NM_001282598; NM_001282599; NM_001282600;
	NM_004389; NM_001320810; NM_001399737
	NM_001109764; NM_009819; NM_145732; NM_001355193
NP_001158355; NP_001269526; NP_001269527; NP_001269528; NP_001269529;
	NP_001307739; NP_004380
	NP_001103234; NP_033949; NP_663785; NP_001342122
	Wikidata
View/Edit Human	View/Edit Mouse

Catenin alpha-2, also known as αN-catenin, is a type of α-catenin protein that in humans is encoded by the CTNNA2 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000066032 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063063 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Claverie JM, Hardelin JP, Legouis R, Levilliers J, Bougueleret L, Mattei MG, Petit C (January 1993). "Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin)". Genomics. 15 (1): 13–20. doi:10.1006/geno.1993.1004. PMID 8432524.
↑ "Entrez Gene: CTNNA2 catenin alpha 2".

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000066032 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063063 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid_8432524-5] Claverie JM, Hardelin JP, Legouis R, Levilliers J, Bougueleret L, Mattei MG, Petit C (January 1993). "Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin)". Genomics. 15 (1): 13–20. doi:10.1006/geno.1993.1004. PMID 8432524.

[entrez-6] "Entrez Gene: CTNNA2 catenin alpha 2".

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Catenin alpha-2

References