// Workers AI · dad joke modeWhat did Bridging integrator 2 say? "I'm connecting the dots.

BIN2
Identifiers
Aliases	BIN2, BRAP-1, bridging integrator 2
External IDs	OMIM: 605936; MGI: 3611448; HomoloGene: 22965; GeneCards: BIN2; OMA:BIN2 - orthologs
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4AVM, 4I1Q
Gene location (Human)
Chr.	Chromosome 12 (human)
End	51,324,668 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	100,567,434 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; blood; ; bone marrow cell; ; spleen; ; trabecular bone; ; lymph node; ; appendix; ; right lung; ; upper lobe of left lung;
	Top expressed in
	granulocyte; ; secondary oocyte; ; spleen; ; thymus; ; primary oocyte; ; placenta; ; zygote; ; bone marrow; ; yolk sac; ; testicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phospholipid binding;
Cellular component	cytoplasm; podosome; cell junction; plasma membrane; cell projection; cell cortex; phagocytic cup; membrane; extracellular region; secretory granule lumen; ficolin-1-rich granule lumen;
Biological process	cell chemotaxis; podosome assembly; phagocytosis, engulfment; plasma membrane tubulation; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	51411
	668218
	ENSG00000110934
	ENSMUSG00000098112
	Q9UBW5
	D3Z6Q9
NM_001290007; NM_001290008; NM_001290009; NM_016293; NM_001364779;
	NM_001364780; NM_001364781
	NM_001270537; NM_001368666
NP_001276936; NP_001276937; NP_001276938; NP_057377; NP_001351708;
	NP_001351709; NP_001351710
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Bridging integrator 2 is a protein that in humans is encoded by the BIN2 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000110934 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000098112 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Bridging integrator 2". Retrieved 2018-05-10.

PDBe-KB provides an overview of all the structure information available in the PDB for Human Bridging integrator 2

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by adding missing information.